DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31548 and Dhrs4

DIOPT Version :9

Sequence 1:	NP_730974.1	Gene:	CG31548 / 318794	FlyBaseID:	FBgn0051548	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_001033027.2	Gene:	Dhrs4 / 28200	MGIID:	90169	Length:	279	Species:	Mus musculus

Alignment Length:	248	Identity:	74/248 - (29%)
Similarity:	132/248 - (53%)	Gaps:	7/248 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 AGKVVLITGASSGIGAATAIKFAKYGACLALNGRNVENLKKVAAECSKVSQSQPALVVGDIAKEA 68
            :.||.|:|.::.|||.|.|.:.|:.||.:.::.|..:|:.:..|.......|...:|. .:.|..
Mouse    32 SNKVALVTASTDGIGFAIARRLAEDGAHVVVSSRKQQNVDRAVATLQGEGLSVTGIVC-HVGKAE 95

  Fly    69 DTQRIWSETLQQYGKLDVLVNNAGIIE-TGTIETTSLEQYDRVMNTNLRAIYHLTMLATPELVKT 132
            |.:::.:..|:::..:|:||:||.:.. .|.:...:.|.:|:|::.|:.|...:.....||:.|.
Mouse    96 DREKLITTALKRHQGIDILVSNAAVNPFFGNLMDVTEEVWDKVLSINVTATAMMIKAVVPEMEKR 160

  Fly   133 -KGNIVNVSSVNGIRSFPGVLAYNISKMGVDQFTRCVALELAAKGVRVNCVNPGVTVTNLHARGG 196
             .|::|.|.||.|...||.:..||:||..:...|:..|.|||.|.:||||:.||:..|.. :...
Mouse   161 GGGSVVIVGSVAGFTRFPSLGPYNVSKTALLGLTKNFAAELAPKNIRVNCLAPGLIKTRF-SSVL 224

  Fly   197 MDAETYKKFLEHSKTTHALGRPGDVKEVAAAIAFLASDEASFSTGVSLPVDGG 249
            .:.:..:.|::.:.....||:|.|   .|..::||.|::||:..|.::.|.||
Mouse   225 WEEKAREDFIKEAMQIRRLGKPED---CAGIVSFLCSEDASYINGETVVVGGG 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31548	NP_730974.1	fabG	1..250	CDD:235975	74/248 (30%)
CG31548	NP_730974.1	NADB_Rossmann	3..253	CDD:304358	74/248 (30%)
Dhrs4	NP_001033027.2	CR_SDR_c	24..279	CDD:187641	74/248 (30%)
		fabG	31..274	CDD:235975	72/246 (29%)
		Microbody targeting signal	277..279
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830573
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740