DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31548 and Dhrs4

DIOPT Version :9

Sequence 1:	NP_730974.1	Gene:	CG31548 / 318794	FlyBaseID:	FBgn0051548	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_695227.2	Gene:	Dhrs4 / 266686	RGDID:	708482	Length:	279	Species:	Rattus norvegicus

Alignment Length:	255	Identity:	78/255 - (30%)
Similarity:	129/255 - (50%)	Gaps:	21/255 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 AGKVVLITGASSGIGAATAIKFAKYGACLALNGRNVENLKKVAAECSKVSQSQPALVVGDIAKEA 68
            |.||.|:|.::.|||.|.|.:.|:.||.:.::.|..:|:.:..|.......|... ||..:.|..
  Rat    32 ANKVALVTASTDGIGLAIARRLAEDGAHVVISSRKQQNVDRAVATLQGEGLSVTG-VVCHVGKAE 95

  Fly    69 DTQRIWSETLQQYGKLDVLVNNAGIIE-TGTIETTSLEQYDRVMNTNLRAIYHLTMLATPELVKT 132
            |.:::.:..|:.:..:|:||:||.:.. .|.:...:.|.:::|::.|:.|...:.....|.:.|.
  Rat    96 DREKLVNMALKLHQGIDILVSNAAVNPFFGNLMDVTEEVWNKVLSINVTASAMMIKAVVPAMEKR 160

  Fly   133 -KGNIVNVSSVNGIRSFPGVLAYNISKMGVDQFTRCVALELAAKGVRVNCVNPGVTVTNL----- 191
             .|::|.||||.|...||.:..||:||..:...|:..|.|||.|.:||||:.||:..|:.
  Rat   161 GGGSVVIVSSVAGFVLFPSLGPYNVSKTALLGLTKNFAAELAPKNIRVNCLAPGLIKTHFSSVLW 225

  Fly   192 --HARGGMDAETYKKFLEHSKTTHALGRPGDVKEVAAAIAFLASDEASFSTGVSLPVDGG 249
              .||..|..||.:        ...||:|.|   ....::||.|::||:..|.::.|.||
  Rat   226 KEKAREEMIKETMQ--------IRRLGKPED---CVGIVSFLCSEDASYINGETVVVGGG 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31548	NP_730974.1	fabG	1..250	CDD:235975	78/255 (31%)
CG31548	NP_730974.1	NADB_Rossmann	3..253	CDD:304358	78/255 (31%)
Dhrs4	NP_695227.2	CR_SDR_c	24..279	CDD:187641	78/255 (31%)
Dhrs4	NP_695227.2	Microbody targeting signal	277..279
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334285
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.740