Protein Alignment CG31548 and DHRS1

DIOPT Version :9

• Sequence 1: NP_730974.1
• Gene: CG31548 / 318794
• FlyBaseID: FBgn0051548
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_001129522.1
• Gene: DHRS1 / 115817
• HGNCID: 16445
• Length: 313
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 78/264 - (29%)
• Similarity: 119/264 - (45%)
• Gaps: 43/264 - (16%)

  Fly     1 MNFAGKVVLITGASSGIGAATAIKFAKYGACLALNGRNVENLKKVAAECSKVSQSQPALVVGDIA 65
            ||  |:|.::||||.|||...|::..|.||.:.:.||:::.|:.||.|...:. .|...||.|.:
Human     5 MN--GQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLG-GQCVPVVCDSS 66

  Fly    66 KEADTQRIWSET-LQQYGKLDVLVNNA-----GIIET--GTIETTSLEQYDRVMNTNLRAIYHLT 122
            :|::.:.::.:. .:|.|:||||||||     .|:.|  .....|....:|.:.|..||..|..:
Human    67 QESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVGLRGHYFCS 131

  Fly   123 MLATPELVKT-KGNIVNVSSVNGIRSFPGVL------AYNISKMGVDQFTRCVALELAAKGVRVN 180
            :.....:|.. :|.||.:||       ||.|      .|.:.|...|:.....|.||...|  |:
Human   132 VYGARLMVPAGQGLIVVISS-------PGSLQYMFNVPYGVGKAACDKLAADCAHELRRHG--VS 187

  Fly   181 CVN--PGVTVTNLHARGGMDAETYKKFLEHSKTTHALGRPGDVKEVAAAIAFLASDEASFSTGVS 243
            ||:  ||:..|.|             ..||......|..| .:|:..:|.:...:.|.|....|:
Human   188 CVSLWPGIVQTEL-------------LKEHMAKEEVLQDP-VLKQFKSAFSSAETTELSGKCVVA 238

  Fly   244 LPVD 247
            |..|
Human   239 LATD 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31548	NP_730974.1	fabG	1..250	CDD:235975	78/264 (30%)
		NADB_Rossmann	3..253	CDD:304358	76/262 (29%)
DHRS1	NP_001129522.1	PRK08303	1..271	CDD:236229	78/264 (30%)
		DHRS1-like_SDR_c	5..271	CDD:187664	78/264 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140608
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740