Protein Alignment CG31548 and DHRS4

DIOPT Version :9

• Sequence 1: NP_730974.1
• Gene: CG31548 / 318794
• FlyBaseID: FBgn0051548
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_066284.2
• Gene: DHRS4 / 10901
• HGNCID: 16985
• Length: 278
• Species: Homo sapiens
• Alignment Length: 251
• Identity: 80/251 - (31%)
• Similarity: 137/251 - (54%)
• Gaps: 13/251 - (5%)

  Fly     4 AGKVVLITGASSGIGAATAIKFAKYGACLALNGRNVENLKKVAAECSKVSQSQPALVVG---DIA 65
            |.||.|:|.::.|||.|.|.:.|:.||.:.::.|..:|:.:..|    ..|.:...|.|   .:.
Human    31 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVA----TLQGEGLSVTGTVCHVG 91

  Fly    66 KEADTQRIWSETLQQYGKLDVLVNNAGIIE-TGTIETTSLEQYDRVMNTNLRAIYHLTMLATPEL 129
            |..|.:|:.:..::.:|.:|:||:||.:.. .|:|...:.|.:|:.::.|::|...:|....||:
Human    92 KAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKAVVPEM 156

  Fly   130 VKT-KGNIVNVSSVNGIRSFPGVLAYNISKMGVDQFTRCVALELAAKGVRVNCVNPGVTVTNLHA 193
            .|. .|::|.|||:......||...||:||..:...|:.:|:|||.:.:||||:.||:..|:...
Human   157 EKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSR 221

  Fly   194 RGGMDAETYKKFLEHSKTTHALGRPGDVKEVAAAIAFLASDEASFSTGVSLPVDGG 249
            ...||.|..    |..|.|..:.|.|:.::.|..::||.|::||:.||.::.|.||
Human   222 MLWMDKEKE----ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGG 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31548	NP_730974.1	fabG	1..250	CDD:235975	80/251 (32%)
		NADB_Rossmann	3..253	CDD:304358	80/251 (32%)
DHRS4	NP_066284.2	CR_SDR_c	23..278	CDD:187641	80/251 (32%)
		fabG	30..273	CDD:235975	78/249 (31%)
		Microbody targeting signal	276..278

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140602
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.740