DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31548 and dhrs7c

DIOPT Version :9

Sequence 1:	NP_730974.1	Gene:	CG31548 / 318794	FlyBaseID:	FBgn0051548	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	XP_012826975.2	Gene:	dhrs7c / 100135266	XenbaseID:	XB-GENE-5956201	Length:	704	Species:	Xenopus tropicalis

Alignment Length:	244	Identity:	70/244 - (28%)
Similarity:	110/244 - (45%)	Gaps:	22/244 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KVVLITGASSGIGAATAIKFAKYGACLALNGRNVENLKKVAAECSKVSQSQ----PALVVGDIAK 66
            |||:||.|.||:|...:..|...||.|.|.|:..|.|:.:......|:...    |.||:.||:.
Frog    38 KVVVITDAISGLGKECSRVFHSAGARLVLCGKTWEKLEALHDALISVADPSVTFTPKLVLLDISD 102

  Fly    67 EADTQRIWSETLQQYGKLDVLVNNAGIIETGTIETTSLEQYDRVMNTNLRAIYHLTMLATPELVK 131
            ..:.:.:..|....||.:|||:|||.:...|.:::.|||...::|:.|......|.....|.::.
Frog   103 INNMEAMGKEIQDCYGCVDVLINNASMKMKGPLQSVSLELDKKIMDANYFGPITLVKAILPHMIS 167

  Fly   132 TK-GNIVNVSSVNGIRSFPGVLAYNISKMGVDQFTRCVALELAAKGVRVNCVNPGVTVTNLHAR- 194
            .: |.||.|:::.|....|...||..||..:..|..|:..|:....|.|:.|:| ..:.:.|.:
Frog   168 RRTGQIVLVNTIQGKIGVPFRAAYAASKHAIQGFFDCLRAEVEEFDVSVSTVSP-TFIRSYHVQP 231

  Fly   195 --GGMDAETYKKFL------------EHSKTTHALGRPG-DVKEVAAAI 228
              |..:|..:|...            ...:.|.|.|.|. :|:|.|.||
Frog   232 QPGNWEASIWKWIFYRVAMESPACVASRGQGTAAHGAPTCNVQEKANAI 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31548	NP_730974.1	fabG	1..250	CDD:235975	70/244 (29%)
CG31548	NP_730974.1	NADB_Rossmann	3..253	CDD:304358	70/244 (29%)
dhrs7c	XP_012826975.2	11beta-HSD1_like_SDR_c	35..257	CDD:187593	61/219 (28%)
dhrs7c	XP_012826975.2	LAP2alpha	425..629	CDD:371604
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910