DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17440 and Kmt2e

DIOPT Version :9

Sequence 1:NP_572555.1 Gene:CG17440 / 31879 FlyBaseID:FBgn0030120 Length:366 Species:Drosophila melanogaster
Sequence 2:NP_081260.1 Gene:Kmt2e / 69188 MGIID:1924825 Length:1868 Species:Mus musculus


Alignment Length:185 Identity:52/185 - (28%)
Similarity:74/185 - (40%) Gaps:27/185 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    20 FDLP--ERKSKIATILKQKDREY------CICRSSDCSRFMIGCDGCEEWYHGDCIEITEKDAEH 76
            |..|  :..|...||...:|..|      |||..:....:||.||.|..|.|.||:.|   |.:|
Mouse    92 FTTPNFDETSSATTISTSEDGSYGTDVTRCICGFTHDDGYMICCDKCSVWQHIDCMGI---DRQH 153

  Fly    77 IKN-YYCRRCKKENPELQTIFRLVATERAAASNAASTSLNAPGVGPSGAAPAAAPVAPATTSQQA 140
            |.: |.|.||:..:.:.:   |.|..:|....|.:....:|...|..      .||...|..|..
Mouse   154 IPDTYLCERCQPRSLDKE---RAVLLQRRKRENMSDGDTSATESGDE------VPVELYTAFQHT 209

  Fly   141 PPPTTAAAKR--KNSSAQEPKESQPTQAGTKRDKA----APKTSNVQVSPRAVSP 189
            |...|..|.|  |.:..:..|..:..|..:|..||    :.|:|.|:.|...:.|
Mouse   210 PTSITLTASRVPKVTDKRRKKSGEKEQNFSKCKKAFREGSRKSSRVKGSAPEIDP 264

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17440NP_572555.1 PHD_Cfp1 40..85 CDD:277028 19/51 (37%)
zf-CpG_bind_C 231..>278 CDD:289071
Kmt2eNP_081260.1 HCFC1-binding motif (HBM). /evidence=ECO:0000250|UniProtKB:Q8IZD2 63..66
PHD_MLL5 120..163 CDD:277025 18/45 (40%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 178..197 4/18 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 217..268 13/48 (27%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 308..329
SET_KMT2E 323..451 CDD:380959
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 472..504
Smc 483..>716 CDD:224117
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 646..682
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 884..924
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1038..1068
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1165..1222
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1236..1315
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1334..1565
Herpes_BLLF1 <1350..1609 CDD:282904
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1585..1842
PRK03427 <1749..>1857 CDD:235124
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0 Normalized mean entropy S6159
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.950

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