DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17440 and E(bx)

DIOPT Version :9

Sequence 1:	NP_572555.1	Gene:	CG17440 / 31879	FlyBaseID:	FBgn0030120	Length:	366	Species:	Drosophila melanogaster
Sequence 2:	NP_001261188.1	Gene:	E(bx) / 44811	FlyBaseID:	FBgn0000541	Length:	2761	Species:	Drosophila melanogaster

Alignment Length:	506	Identity:	105/506 - (20%)
Similarity:	169/506 - (33%)	Gaps:	183/506 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 IRREIAREFDLPERKSKIATI---LKQKDREYCICRSSDCSRFMIGCDGCEEWYHGDCIEITEKD 73
            :||::....::|:...::.:|   |:::.|    ..|...:...|    .|||...|.:|:.|
  Fly  1385 LRRKVVIPLEMPKTVREVTSIRSGLRKRKR----AESPQPTEPQI----TEEWVDEDKLELWE-- 1439

  Fly    74 AEHIKNYYCRRCKKENPELQTIFRLVATER--AAASNAASTSLN-APGV---------------- 119
               ||   ....|:|...|..:.|.||:.:  |:.||.::||.| |.||
  Fly  1440 ---IK---FMGEKQEKARLSAVTRSVASRQLEASGSNGSNTSTNGALGVAGRVQLAPKLSEDVKE 1498

  Fly   120 ----------------------------------------------------------------G 120
                                                                            |
  Fly  1499 KMEQQLKLQRAVHQQRKLVATGEITRSVTPVKGQVIGSRRVIVKNPDGTTRIIQQAVTQVSRTGG 1563

  Fly   121 PSGAAPAAAPVAPATTSQQAPPPTTAAAKRKNSSAQEPKES----QPTQ---------------- 165
            .:.||.||:|....:||.|:.|.|:...|.:.....:.|.|    .|.|
  Fly  1564 ANTAAAAASPTVGGSTSTQSNPSTSTPHKVQIIRGPDGKVSVRGLNPGQQLVQMPDGKLHVLTTT 1628

  Fly   166 -----AGTKRDKAAP-KTSNVQVSPRAVSPEIFLNPELQGIQQCHGPNCCSHARPQSKYCSDECG 224
                 ||.......| |.::...||...|.:...||....|:|....:...::..||...|....
  Fly  1629 TSSNSAGQGNKMKVPIKPASTSSSPAISSAQTTTNPVTPVIKQIAVKHVTKNSATQSIASSSRVA 1693

  Fly   225 SNLA-IERLFQILPQQMQEWNITPSRAAEETRKHLELNMDELVLKQQEQLEEFEKQRQQIQTQQ- 287
            ..|| |:....:..||.|..:.:|:.::...:|         ::.:........:..||:..|.
  Fly  1694 LPLAQIKNKLLLAQQQQQSTSSSPATSSSPVQK---------IVSKVVNTSTSGQTLQQVFVQSG 1749

  Fly   288 -----KQYQEKQKLMLQQQPQQQQ-----QQQELQQQQELQQQQEQ------------------- 323
                 .|..:.||:::.....|||     |||:|.|.|.:||..:|
  Fly  1750 SKLVVGQNAQGQKVIISTSAAQQQGTSPVQQQQLVQSQPIQQSPQQISMTQVGNQPTQKVIQQIV 1814

  Fly   324 ----EQQQLL---QQLHLKP-------HHVQQLQLQMQLLQQQRQLLQQQQ 360
                .|||::   |::.|.|       .:|.|.| .:|::|||.|..||||
  Fly  1815 NTSNVQQQIVVGGQRIILSPGQTIVTQRNVPQSQ-ALQMVQQQIQTQQQQQ 1864

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17440	NP_572555.1	PHD_Cfp1	40..85	CDD:277028	10/44 (23%)
CG17440	NP_572555.1	zf-CpG_bind_C	231..>278	CDD:289071	5/46 (11%)
E(bx)	NP_001261188.1	DDT	190..245	CDD:280886
		WHIM1	288..337	CDD:292246
		PHD1_BPTF	341..383	CDD:277034
		BAH	361..>438	CDD:295389
		TNG2	<2423..2638	CDD:227367
		PHD_SF	2533..2579	CDD:304600
		PHD2_3_BPTF	2589..2635	CDD:277035
		Bromo_gcn5_like	2653..2752	CDD:99941
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1632
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900