DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17440 and set-26

DIOPT Version :9

Sequence 1:	NP_572555.1	Gene:	CG17440 / 31879	FlyBaseID:	FBgn0030120	Length:	366	Species:	Drosophila melanogaster
Sequence 2:	NP_001370101.1	Gene:	set-26 / 178463	WormBaseID:	WBGene00013106	Length:	1645	Species:	Caenorhabditis elegans

Alignment Length:	402	Identity:	72/402 - (17%)
Similarity:	150/402 - (37%)	Gaps:	106/402 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KKTEEEIRREIA---REFDLPER----------KSKIATILKQKDREYCICR------------- 44
            ::.|||:|||.|   ::.|..|:          |.|     |.|:||....|
Worm  1121 RRLEEEVRRERAAKTKQMDEAEKARLEAEKAAEKEK-----KAKEREEAKERKKMEVEASAAAAP 1180

  Fly    45 ---SSDCSRFMIGCDGCEEWYHGDCIEITEKDAEHIKNYYCRRCKKENPELQTIFRLVATERAAA 106
               :|..:|........||.:.....|...|:|.       ||.|...|.:     |.|...||.
Worm  1181 ESSNSITAREERRIQQAEEMFRRQEEEGKRKEAR-------RRSKSVTPGV-----LEAAGTAAR 1233

  Fly   107 SNAASTSLNAPGVGPSGAAPAAAPVAPATTSQQAPPPTTAAAKRKNSSAQEPKESQP-------- 163
            .:|...|:.||...|..:..:.:.....:||..| .||...||.|...:..|.:|:|
Worm  1234 EDAPEASIPAPAPSPPASRRSVSRTTQPSTSSFA-TPTEPPAKNKRMRSVVPPKSEPASSAKRVR 1297

  Fly   164 -TQAGTKRDKAAPKTSNVQVSPRAVSPEIFLNPELQGIQQCHGPNCCSHARPQSKYCSDECGSNL 227
             |...|.:|..|...|..:.|                        ..:...|.:|...:...::.
Worm  1298 ATTVATPKDTTASNDSRKRKS------------------------SATGKTPVAKRSKNVVPTSF 1338

  Fly   228 AIERLFQILPQQMQEWNITPSRAAEETRKHLELNMDELVLKQQE------QLEEFEKQRQQIQTQ 286
            .:..:.:.|.:|.::..:            ||:.:.:.::|::.      |..:|.:.|.||
Worm  1339 GLALIEKELREQARDSTV------------LEMILPDYIMKEKRSGLLAGQSPDFSEVRAQI--- 1388

  Fly   287 QKQYQEKQKLMLQQQPQQQQQQQELQQQQELQQQQEQEQQQLLQQLHLKPHHVQQLQLQMQLLQQ 351
                 |::..|.::..:::.:::.:::.:|.::::.:::.:...:....|...:.::..::.:::
Worm  1389 -----EEENRMKERFTKREAKKKAVEKAKEKEKKEHRKEPKKANEPGPAPKSEKAVEKAVEKVEK 1448

  Fly   352 QRQLLQQQQHKP 363
            :.:..|:...||
Worm  1449 KPKSPQKPPAKP 1460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17440	NP_572555.1	PHD_Cfp1	40..85	CDD:277028	9/60 (15%)
CG17440	NP_572555.1	zf-CpG_bind_C	231..>278	CDD:289071	7/52 (13%)
set-26	NP_001370101.1	PRK03427	<9..>135	CDD:235124
		PHD_Bye1p_SIZ1_like	796..839	CDD:277045
		SET_SETD5-like	935..1067	CDD:380927
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6159
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950