Protein Alignment CG17440 and DIDO1

DIOPT Version :10

• Sequence 1: NP_572555.1
• Gene: CG17440 / 31879
• FlyBaseID: FBgn0030120
• Length: 366
• Species: Drosophila melanogaster
• Sequence 2: NP_149072.2
• Gene: DIDO1 / 11083
• HGNCID: 2680
• Length: 2240
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 65/248 - (26%)
• Similarity: 93/248 - (37%)
• Gaps: 77/248 - (31%)

  Fly     7 KTEEEIRREIAREFDLPERKSKIATILKQ--KDRE-------------------YCICRSSDCSR 50
            |.|.|..:.:..:....:|:||:.....|  ||.|                   |||||....:|
Human   216 KQEPENDQGVVSQAGKDDRESKLEGKAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNR 280

  Fly    51 FMIGCDGCEEWYHGDCIEITEKDAEHI----KNYYCRRCKKENPELQTIFRL---VATERAAASN 108
            |||.||.||||:||||:.|:|.....:    ::|.|..|        ||.::   ..:|.|....
Human   281 FMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNC--------TILQVQDETHSETADQQE 337

  Fly   109 AASTSLNAPGVGPSGAAPAAAPVAPATTSQQAPPPTTAAAKRKNSSAQEPK---ESQPTQAGTKR 170
            |.....:|.|...:                     :....::|:|..|..|   |.....:|.|:
Human   338 AKWRPGDADGTDCT---------------------SIGTIEQKSSEDQGIKGRIEKAANPSGKKK 381

  Fly   171 DKAAPKTSNVQVSPRAVSPEIFLNPELQGIQQCHGPNCCSHARPQSKYCSDEC 223
            .|             ...|.|    |..|..:|.||.||..|:|.|.|||::|
Human   382 LK-------------IFQPVI----EAPGASKCIGPGCCHVAQPDSVYCSNDC 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17440	NP_572555.1	PHD_Cfp1	40..85	CDD:277028	23/48 (48%)
		CpG_bind_C	228..>278	CDD:463514
DIDO1	NP_149072.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..259		10/42 (24%)
		TNG2	<160..302	CDD:227367	30/85 (35%)
		Nuclear localization signal. /evidence=ECO:0000255	165..173
		Nuclear localization signal. /evidence=ECO:0000255	185..193
		PHD_DIDO1_like	266..319	CDD:277109	23/52 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	431..456
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	501..567
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	584..618
		TFS2M	672..773	CDD:128786
		PHA03247	<773..1044	CDD:223021
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	773..826
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	860..947
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1013..1045
		SPOC_DIDO1-like	1056..1198	CDD:439210
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1206..1427
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1453..1472
		SWIRM-assoc_1	<1469..1507	CDD:465142
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1517..2240
		PHA03247	<1525..2054	CDD:223021
		SF-CC1	2125..>2230	CDD:273721