Protein Alignment CG31533 and Krt19

DIOPT Version :10

• Sequence 1: NP_731887.1
• Gene: CG31533 / 318788
• FlyBaseID: FBgn0051533
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_032497.1
• Gene: Krt19 / 16669
• MGIID: 96693
• Length: 403
• Species: Mus musculus
• Alignment Length: 213
• Identity: 45/213 - (21%)
• Similarity: 83/213 - (38%)
• Gaps: 42/213 - (19%)

  Fly    18 IFGVTIDEPAKLLVETKVAGKSVKVTSSRINVDQFVAGREFELPMEASTLRQSLEEKGLTLAGVY 82
            |.|.|||. :|::::         :.::|:..|.|....|.|     ..||.|:|.....|..|.
Mouse   144 ILGATIDN-SKIVLQ---------IDNARLAADDFRTKFETE-----HALRLSVEADINGLRRVL 193

  Fly    83 QGSTLGKATGNFPVEFL-DKISPTMNDLVHEDTLDLVRRVDVVGTVSVLIRLTVKCEEHPEQKPS 146
            ...||.:......:|.| ::::....:  ||:.:..:|. .|.|.|||.:..|      |....:
Mouse   194 DELTLARTDLEMQIESLKEELAYLKKN--HEEEITALRS-QVGGQVSVEVDST------PGVDLA 249

  Fly   147 RQSLSRTSKSSMILPKKEKSGRVSCASQGPTFNPQDVMFLIGDPDPLLRIPSEPCSELLSEIGDE 211
            :......|:..::..|..|....:..::....|.|            :.:.||......:|:.|.
Mouse   250 KILSEMRSQYEIMAEKNRKDAEATYLARIEELNTQ------------VAVHSEQIQISKTEVTDL 302

  Fly   212 R-----LKLDLQRYKSLE 224
            |     |:::||...|::
Mouse   303 RRTLQGLEIELQSQLSMK 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31533	NP_731887.1	DUF4788	12..260	CDD:406440	45/213 (21%)
		DUF4776	315..758	CDD:406413
Krt19	NP_032497.1	Head	1..82
		Filament	82..393	CDD:459643	45/213 (21%)
		Coil 1A	83..118
		Linker 1	119..136
		Coil 1B	137..228		23/100 (23%)
		Linker 12	229..251		8/28 (29%)
		Necessary for interaction with PNN. /evidence=ECO:0000250	247..393		14/86 (16%)
		Coil 2	252..390		14/81 (17%)
		Rod-like helical tail	391..403