DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31524 and P4htm

DIOPT Version :9

Sequence 1:	NP_733379.2	Gene:	CG31524 / 318781	FlyBaseID:	FBgn0051524	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_083220.3	Gene:	P4htm / 74443	MGIID:	1921693	Length:	503	Species:	Mus musculus

Alignment Length:	389	Identity:	91/389 - (23%)
Similarity:	139/389 - (35%)	Gaps:	131/389 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   201 KGPQTEMILLRGPTKAELFRTLGKVRFERRNEEGALKAYQAALKHSPHDLEIFQEYQNLKRRVLT 265
            ||.|...||   ||:               ..|.|:.|.|.:      .|::||          .
Mouse   167 KGLQRSQIL---PTE---------------EYEEAMSAMQVS------QLDLFQ----------L 197

  Fly   266 LSPSEPIREEPNDDIEEMELPPCCSGRCEGPRKLNRLYCVYNCVTAPFLRLAPIKTEILSVDPFV 330
            |..:...|.:..:.:.:..|.   :||...|..:..:|..        ::..|....:||:..|.
Mouse   198 LDQNHDGRLQLREVLAQTRLG---NGRWMTPENIQEMYSA--------IKADPDGDGVLSLQEFS 251

  Fly   331 IL-LHD----MVSHKEGALIRSSSKNQILPSETVNAANEFEIAKFRTSKSVWF--DSDANEATLK 388
            .: |.|    |.|||       :..|:::                |.|...|.  ...|:.....
Mouse   252 NMDLRDFHKYMRSHK-------AESNELV----------------RNSHHTWLHQGEGAHHVMRA 293

  Fly   389 LTQRLGEATGLD---MKHSEPFQVINYGIGGVFESHFDT------SLADEDRFV-NGYID----- 438
            :.||:...|.|.   ::.|||.||:.||.||.:.:|.|:      ::....:.| |..:.
Mouse   294 IRQRVLRLTRLSPEIVEFSEPLQVVRYGEGGHYHAHVDSGPVYPETICSHTKLVANESVPFETSC 358

  Fly   439 RLATTLFYLNDVPQGGATHFPGL---------------------------NITVFPKFGTVLMWY 476
            |..|.|||||:|..||.|.||..                           |:.|.|:.||.:.||
Mouse   359 RYMTVLFYLNNVTGGGETVFPVADNRTYDEMSLIQDDVDLRDTRRHCDKGNLRVKPQQGTAVFWY 423

  Fly   477 NLHTEGMLHV-----RTMHTGCPVIVGSKWVVSKWID-DKG--------QEFRRPCLRSRLDSK 526
            |...:|...|     .::|.||.|..|:||:.:.||: |..        ||..|......:||:
Mouse   424 NYLPDGQGWVGEVDDYSLHGGCLVTRGTKWIANNWINVDPSRARQALFQQEMARLAREGGMDSQ 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31524	NP_733379.2	P4Ha_N	31..157	CDD:285528
		TPR_11	215..>259	CDD:290150	7/43 (16%)
		TPR_2	216..249	CDD:285020	4/32 (13%)
		P4Hc	340..507	CDD:214780	53/215 (25%)
P4htm	NP_083220.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..49
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	90..110
		EF-hand_7	193..253	CDD:290234	13/80 (16%)
		EFh	195..253	CDD:298682	13/78 (17%)
		P4Hc	247..459	CDD:214780	59/234 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839376
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740