DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31524 and Y43F8B.19

DIOPT Version :9

Sequence 1:	NP_733379.2	Gene:	CG31524 / 318781	FlyBaseID:	FBgn0051524	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_001123044.2	Gene:	Y43F8B.19 / 6418801	WormBaseID:	WBGene00077688	Length:	243	Species:	Caenorhabditis elegans

Alignment Length:	234	Identity:	57/234 - (24%)
Similarity:	92/234 - (39%)	Gaps:	42/234 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   319 IKTEILSVDPFVILLHDMVSHK--------------EGALIRSSSKNQILPSETVNAANEFEI-- 367
            :|.|:::..|.:::..|:.:.|              |..|:.:...|.|:  ..:..||..::
Worm    22 VKVEVVAWRPGLVIYRDLFTGKQVRDHLELMEHLKFEEQLVVNDDGNDIV--SKIRRANGTQVFH 84

  Fly   368 AKFRTSKSVWFDSDANEATLKLTQRLGEATGLDMKHSEPFQVINYGIGGVFESHFDTSLA----- 427
            .....::|:| |:..|           ....|:.|.:|....::|..||.:.:|.|..|.
Worm    85 EDHPAARSIW-DTAKN-----------LLPNLNFKTAEDILALSYNPGGHYAAHHDYLLYPSEKE 137

  Fly   428 -DEDRFVNGYIDRLATTLFYLNDVPQGGATHFPGLNITVFPKFGTVLMWYNLHTEGMLHVRTMHT 491
             ||...|||  :|..|.:........||||.||.|...|..|.|....|:|..........:.|.
Worm   138 WDEWMRVNG--NRFGTLIMAFGAAESGGATVFPRLGAAVRTKPGDAFFWFNAMGNSEQEDLSEHA 200

  Fly   492 GCPVIVGSKWVVSKWIDDKGQEFRRPCLRSRLDSKYLSS 530
            |||:..|.|.:.:.|:..:.|    |.|...|.|..||:
Worm   201 GCPIYKGQKQISTIWLRMRDQ----PILEQTLSSDSLSA 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31524	NP_733379.2	P4Ha_N	31..157	CDD:285528
		TPR_11	215..>259	CDD:290150
		TPR_2	216..249	CDD:285020
		P4Hc	340..507	CDD:214780	45/188 (24%)
Y43F8B.19	NP_001123044.2	P4Hc	43..217	CDD:214780	46/189 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810