Protein Alignment CG31524 and PH4alphaNE2

DIOPT Version :9

• Sequence 1: NP_733379.2
• Gene: CG31524 / 318781
• FlyBaseID: FBgn0051524
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_733378.1
• Gene: PH4alphaNE2 / 43628
• FlyBaseID: FBgn0039783
• Length: 542
• Species: Drosophila melanogaster
• Alignment Length: 539
• Identity: 313/539 - (58%)
• Similarity: 405/539 - (75%)
• Gaps: 8/539 - (1%)

  Fly     5 KLLFVVIFFLSLSMGQIEA--TQPRFARSVVNMDDLLNMEDDLVSKLEGYAEKLSYKANTIRWGI 67
            :|:.:.:.:||||.||:..  .|.|||||||||||:||:||||||.:|..||.|:.||.||:||:
  Fly     5 RLVLLGMLYLSLSFGQLRENNAQQRFARSVVNMDDMLNLEDDLVSNVEKLAEALARKAKTIKWGV 69

  Fly    68 QQM--REQLDKSKKEQSFDLFNRYSFIRHMQADWLMWKQYLDKPVIRDELNYKQMDNLRMPQELD 130
            .:|  |.|..||..|...:..:.:|.|||||::||||..||:.||.::||.:.......:|:..|
  Fly    70 FKMMKRRQEYKSSMEIFANPIDTFSLIRHMQSNWLMWLLYLETPVGQEELFFVDSRMPLLPKYFD 134

  Fly   131 LFDASEAIRRMQATYAMLSNDIAEGFLDGVQYTSKLSPIDCLAMGRHLMNQSRWTIAEQWILAGI 195
            ..||:|.||:|||||.|.|:|||:|.||||||.|.|.||||||:|.||||.|||..|||||.|.|
  Fly   135 FIDAAEGIRKMQATYQMFSSDIAKGLLDGVQYNSSLKPIDCLAIGLHLMNNSRWYAAEQWISASI 199

  Fly   196 KAQDRKGPQTEMILLRGPTKAELFRTLGKVRFERRNEEGALKAYQAALKHSPHDLEIFQEYQNLK 260
            :|.|:|..||:|.|||||..|:|.|.||:|:.::||.||||:|||.|||.||||.||::||:.|:
  Fly   200 EAYDQKSSQTDMELLRGPKLADLCRILGQVQMKQRNHEGALQAYQVALKLSPHDPEIYEEYRILE 264

  Fly   261 RRVLTLSPSEPIREEPNDDIEEMELPPCCSGRCEGPRKLNRLYCVYNCVTAPFLRLAPIKTEILS 325
            :|.||||..|||.::.::..|.:.|||||||||:.||.|:.||||||.||:|||:||||||||||
  Fly   265 KRDLTLSDIEPIEQDKDNSHERLVLPPCCSGRCQVPRNLSNLYCVYNHVTSPFLQLAPIKTEILS 329

  Fly   326 VDPFVILLHDMVSHKEGALIRSSSKNQILPSETVN---AANEFEIAKFRTSKSVWFDSDANEATL 387
            :||||:|||||:|.||..|||:|||..:|||.|.:   :.:|.::..:|||||||:.||.|:.|.
  Fly   330 IDPFVVLLHDMISQKESTLIRTSSKEHMLPSATTDPDASDDETQVDTYRTSKSVWYSSDFNDTTK 394

  Fly   388 KLTQRLGEATGLDMKHSEPFQVINYGIGGVFESHFDTSLADEDRFVNGYIDRLATTLFYLNDVPQ 452
            |:|:|||:||||||..:|.:||||||:||.||:|.|..|::::|| ||..||:||||||||:|.|
  Fly   395 KITERLGDATGLDMNSTEFYQVINYGLGGFFETHLDMLLSEKNRF-NGTSDRIATTLFYLNEVRQ 458

  Fly   453 GGATHFPGLNITVFPKFGTVLMWYNLHTEGMLHVRTMHTGCPVIVGSKWVVSKWIDDKGQEFRRP 517
            ||.|:||.||:||||:.|:.|.||||.|:|..|:.::|||||||||||||:||||:|.||||.||
  Fly   459 GGGTYFPRLNLTVFPQPGSALFWYNLDTKGNDHMGSLHTGCPVIVGSKWVMSKWINDMGQEFTRP 523

  Fly   518 CLRSRLDSKYLSSIEKIII 536
            |:.|.|.|..:.|.|::||
  Fly   524 CVESSLSSNEVLSAERLII 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31524	NP_733379.2	P4Ha_N	31..157	CDD:285528	65/127 (51%)
		TPR_11	215..>259	CDD:290150	26/43 (60%)
		TPR_2	216..249	CDD:285020	20/32 (63%)
		P4Hc	340..507	CDD:214780	100/169 (59%)
PH4alphaNE2	NP_733378.1	P4Ha_N	33..161	CDD:285528	65/127 (51%)
		TPR repeat	175..200	CDD:276809	17/24 (71%)
		TPR_16	176..254	CDD:290168	49/77 (64%)
		TPR repeat	219..249	CDD:276809	17/29 (59%)
		TPR_2	220..253	CDD:285020	20/32 (63%)
		P4Hc	342..513	CDD:214780	101/171 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461716
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	10	9.900