DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31524 and CG31371

DIOPT Version :9

Sequence 1:	NP_733379.2	Gene:	CG31524 / 318781	FlyBaseID:	FBgn0051524	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_733375.2	Gene:	CG31371 / 43626	FlyBaseID:	FBgn0051371	Length:	507	Species:	Drosophila melanogaster

Alignment Length:	543	Identity:	121/543 - (22%)
Similarity:	216/543 - (39%)	Gaps:	113/543 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPVLKLLFVVIFFLSLSMGQIEATQPRFARSVVNMDDLLNMEDDLVSKLEGYAEKLSYKANTIR- 64
            |||   :|.|::.|.|.:.........|||....:..||:.|..|:..|..|.|:|..:...||
  Fly     1 MPV---VFSVLWLLQLFLLVESVAGANFARGEEQLQALLDTETQLIDGLRDYIERLERQLEEIRR 62

  Fly    65 --WGIQQMREQLDKSKKEQSFDLFNRYSFIRHMQADWLMWKQYLD---KPVIRDELNYKQMDNLR 124
              ..|:::..|:| |.:|...:..|.:..::..::.|...:|..:   :.|..:.|:.:|   |.
  Fly    63 ETSAIEEIHSQVD-SVEEYMGNPLNVFGILKRFESVWPGLEQKANATLEMVFGERLSDRQ---LT 123

  Fly   125 MPQELDLFDASEAIRRMQATYAMLSNDIAEGFLDGVQYTSKLSPIDCLAMGRHLMNQSRWTIAEQ 189
            :|.|.|..::...:..:|:.|.:.||.::.|.::|.:..|.:|..|||.:.|    :|.:.:|..
  Fly   124 LPSEEDYEESLNHLLHLQSVYELDSNSLSLGVVNGFKLGSSMSWGDCLEVAR----KSDFPVARF 184

  Fly   190 WILAGIKAQDRKGPQTEMILLRGPTKAELFRTLGKVRFERRNEEGALKAYQAALKHSPHDLEIFQ 254
            |:              |..|.:.|:.:|     .....:|..|.|.:...:|.|.......|:.:
  Fly   185 WL--------------ESALEKLPSASE-----NSTESQRERESGRVHILEATLNIEYRAGELSR 230

  Fly   255 EYQNLKRRVLTLSPSEPIREEPNDDIEEM---ELPPCCSGR----------------------CE 294
            .....:..:|.|..::.|::......:.|   |||   .||                      |.
  Fly   231 ALATAEELLLLLPMNQGIQKAKRKIEKAMAKKELP---KGRGQKSKAKKQISKSTEQLLIEEICR 292

  Fly   295 GPRKLNRLYCVYN-CV---TAPFLRLAPIKTEILSVDPFVILLHDMVSHKEGALIRSSSKNQILP 355
            |.::.......:| |.   ::|:|.|.|.:.|.:|.||:::|.||:::.||     |:...|::.
  Fly   293 GAKQQVTTGSRFNHCQLDGSSPWLLLQPSRLEPVSSDPYIVLHHDVLTPKE-----SNELLQLID 352

  Fly   356 SETVNAANEFEIAKFRTSKSVWFDSDANEATLKLTQ-------RLGEATGLDMKHSEPFQVINYG 413
            .|             ..:|.|.:.|      |||::       |:....||::...:|:....:|
  Fly   353 EE-------------EDTKGVSYQS------LKLSKLAQKKLGRISRLLGLEILELDPWTGRRHG 398

  Fly   414 IGGVFESHFDTSLADEDRFVNGYIDRLATTLFYLNDVPQGGATHFPGLNITVFPKFGTVLMWYNL 478
                 ..|. |.|.....     :..:|..:..|.....|||..||.|.:.|....|::|.|...
  Fly   399 -----HEHI-TKLEHSSE-----LKHVARLMLNLQAPGMGGAVVFPQLELAVNVPRGSLLHWRTR 452

  Fly   479 HTEGMLHVRTMHTG---CPVIVG 498
            ...|........:|   |||::|
  Fly   453 FAGGSSSEWDYRSGQAICPVLLG 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31524	NP_733379.2	P4Ha_N	31..157	CDD:285528	30/131 (23%)
		TPR_11	215..>259	CDD:290150	7/43 (16%)
		TPR_2	216..249	CDD:285020	6/32 (19%)
		P4Hc	340..507	CDD:214780	37/169 (22%)
CG31371	NP_733375.2	P4Ha_N	30..156	CDD:285528	30/129 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461803
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	6	5.840