DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31524 and P4ha3

DIOPT Version :9

Sequence 1:	NP_733379.2	Gene:	CG31524 / 318781	FlyBaseID:	FBgn0051524	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	XP_038938408.1	Gene:	P4ha3 / 361612	RGDID:	735150	Length:	549	Species:	Rattus norvegicus

Alignment Length:	469	Identity:	113/469 - (24%)
Similarity:	200/469 - (42%)	Gaps:	82/469 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 YSFIRHMQADWLMWKQYLDKP----VIRDELNYKQMDNLRMPQELDLFDASEAIRRMQATYAMLS 149
            ::.|:.:|:||......|:..    .::|.....:.|   :|...||..|:.|:.|:|..|.:..
  Rat    90 FTLIKRLQSDWRNVVHSLEATENIRALKDGYEKVEQD---LPAFEDLEGAARALMRLQDVYMLNV 151

  Fly   150 NDIAEGFLDGVQYTS-----------KLSPIDCLAMGRHLMNQSRWTIAEQWILAGIKAQDRKGP 203
            ..:|:|....|..:|           .|:..||..:|:...:...:..|..|:...:....|...
  Rat   152 KGLAQGVFQRVTGSSITDLYSPRQLFSLTADDCFQVGKVAYDTGDYYHAIPWLEEAVSLFRRSYG 216

  Fly   204 Q--TEMILLRGPTKAELFRTLGKVRF---ERRNEEGALKAYQAALKHSPHDLEIFQ---EYQNLK 260
            :  ||       .:|.|...|..:.|   :..|...||...:..|.:||.:..:.:   :|:.|.
  Rat   217 EWKTE-------DEASLEDALDYLAFACYQVGNVSCALSLSREFLVYSPDNKRMARNVLKYERLL 274

  Fly   261 RRVLTLSPSEPIREEPNDDIEEMELPPCCSGRCE--GPR----KLNRLYCVYNCVTAPFLRLAPI 319
            .....|..:|...:.||  :..::......|.|:  |.:    ::..|||.|...::|:|.|.|.
  Rat   275 AENGHLMAAETAIQRPN--VPHLQTRDTYEGLCQTLGSQPTHYQIPSLYCSYETNSSPYLLLQPA 337

  Fly   320 KTEILSVDPFVILLHDMVSHKEGALIRSSSKNQILPSETVNAANEFEIAKFRTSKSVWFDSDANE 384
            :.|::.:.|.|.|.||.||.:|...||..::..:..|...:...:.:: ::|.|||.|.....:.
  Rat   338 RKEVIHLRPLVALYHDFVSDEEAQKIRELAEPWLQRSVVASGEKQLQV-EYRISKSAWLKDTVDP 401

  Fly   385 ATLKLTQRLGEATGLDMK--HSEPFQVINYGIGGVFESHFDTSLADED---RFVNGYIDRLATTL 444
            ..:.|.:|:...||||::  ::|..||:||||||.:|.|||.:.:...   :..:|  :|:||.:
  Rat   402 VLVTLDRRIAALTGLDIQPPYAEYLQVVNYGIGGHYEPHFDHATSPSSPLYKMKSG--NRVATLM 464

  Fly   445 FYLNDVPQGGATHFPGLNITVFPKFGTVLMWYNLHTEGMLHVRTMHTGCPVIVGSKWVVSKW--I 507
            .||:.|..||||.|...|.:|                            ||:   ||..|.:  :
  Rat   465 IYLSSVEAGGATAFIYGNFSV----------------------------PVV---KWPTSGYTSM 498

  Fly   508 DDKGQEFRRPCLRS 521
            |...::...|.|::
  Rat   499 DRNSEDPAAPILKT 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31524	NP_733379.2	P4Ha_N	31..157	CDD:285528	17/71 (24%)
		TPR_11	215..>259	CDD:290150	11/49 (22%)
		TPR_2	216..249	CDD:285020	10/35 (29%)
		P4Hc	340..507	CDD:214780	47/173 (27%)
P4ha3	XP_038938408.1	P4Ha_N	34..108	CDD:400573	4/17 (24%)
P4ha3	XP_038938408.1	P4Hc	356..>478	CDD:214780	40/124 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343165
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR10869
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.850