Protein Alignment CG31524 and P4ha2

DIOPT Version :10

• Sequence 1: NP_733379.2
• Gene: CG31524 / 318781
• FlyBaseID: FBgn0051524
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: XP_006532515.1
• Gene: P4ha2 / 18452
• MGIID: 894286
• Length: 557
• Species: Mus musculus
• Alignment Length: 578
• Identity: 172/578 - (29%)
• Similarity: 265/578 - (45%)
• Gaps: 78/578 - (13%)

  Fly     4 LKLLFVVIFFLSLSMGQIEATQPRFARSVVNMDDLLNMEDDLVSKLEGYAEKLSYKANTIRWGIQ 68
            :||..:|:..|....|.:...|..|..|:.:|.||:..|.|||..|:.|......|...|:....
Mouse     1 MKLQVLVLVLLMSWFGVLSWVQAEFFTSIGHMTDLIYAEKDLVQSLKEYILVEEAKLAKIKSWAS 65

  Fly    69 QMREQLDKSKKEQSFDL---FNRYSFIRHMQADWLMWKQYLDKPVIRD----ELNYKQMDNLRM- 125
            :|.....:|..:....|   .|.|..::.:..||         |.:.|    :.:...:.||.:
Mouse    66 KMEALTSRSAADPEGYLAHPVNAYKLVKRLNTDW---------PALGDLVLQDASAGFVANLSVQ 121

  Fly   126 ----PQELDLFDASEAIRRMQATYAMLSNDIAEGFLDGVQYTSKLSPIDCLAMGRHLMNQSRWTI 186
                |.:.|...|:.|:.|:|.||.:..:.|:.|.|.|.:|.:.||..||..:||...|:..:..
Mouse   122 RQFFPTDEDESGAARALMRLQDTYKLDPDTISRGELPGTKYQAMLSVDDCFGLGRSAYNEGDYYH 186

  Fly   187 AEQWILAGIKAQDRKGPQTEMILLRGPTKAELFRTLGKVRFERRNEEGALKAYQAALKHSP-HD- 249
            ...|:...:|..| .|.:..:      ||:.:...|....|:..:...|::..:..|...| |:
Mouse   187 TVLWMEQVLKQLD-AGEEATV------TKSLVLDYLSYAVFQLGDLHRAVELTRRLLSLDPSHER 244

  Fly   250 ----LEIFQEYQNLKR-RVLT------LSPSEPIREEPNDDIEEMEL-PPCCSGRCEG----PRK 298
                |..|:.....:| :.|:      |:..|.:.|.|.|.:.|.:: ...|.|  ||    ||:
Mouse   245 AGGNLRYFERLLEEERGKSLSNQTDAGLATQENLYERPTDYLPERDVYESLCRG--EGVKLTPRR 307

  Fly   299 LNRLYCVY---NCVTAPFLRLAPIKTEILSVDPFVILLHDMVSHKEGALIRSSSKNQILPSETVN 360
            ..:|:|.|   |.|  |.|.:||.|.|.....|.::..:|::|.:|...|:..:|.: |...||.
Mouse   308 QKKLFCRYHHGNRV--PQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK-LARATVR 369

  Fly   361 --AANEFEIAKFRTSKSVWFDSDANEATLKLTQRLGEATGLDMKHSEPFQVINYGIGGVFESHFD 423
              ......:|.:|.|||.|.:.|.:....::.:|:...|||.:|.:|..||.|||:||.:|.|||
Mouse   370 DPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFD 434

  Fly   424 TS--------------LA-------DEDRFVN-GYIDRLATTLFYLNDVPQGGATHFPGLNITVF 466
            .|              ||       ::|.|.. |..:|:||.|.|::||..||||.||.|...::
Mouse   435 FSRRPFDSGLKTEGNRLATFLNYSDEQDAFKRLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIW 499

  Fly   467 PKFGTVLMWYNLHTEGMLHVRTMHTGCPVIVGSKWVVSKWIDDKGQEFRRPCLRSRLD 524
            ||.||.:.||||...|....||.|..|||:||.|||.:||..::||||.|||..:.:|
Mouse   500 PKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGTTEVD 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31524	NP_733379.2	P4Ha_N	31..159	CDD:462433	34/139 (24%)
		BepA	172..>256	CDD:443813	17/89 (19%)
		P4Hc	340..507	CDD:214780	71/190 (37%)
P4ha2	XP_006532515.1	P4Ha_N	28..159	CDD:462433	34/139 (24%)
		P4Hc	348..541	CDD:214780	73/193 (38%)