Protein Alignment CG31524 and P4ha1

DIOPT Version :9

• Sequence 1: NP_733379.2
• Gene: CG31524 / 318781
• FlyBaseID: FBgn0051524
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_001303300.1
• Gene: P4ha1 / 18451
• MGIID: 97463
• Length: 534
• Species: Mus musculus
• Alignment Length: 557
• Identity: 166/557 - (29%)
• Similarity: 269/557 - (48%)
• Gaps: 68/557 - (12%)

  Fly    10 VIFFLSLSMGQIEATQPRFARSVVNMDDLLNMEDDLVSKLEGYAEKLSYKANTI-RWGIQQMREQ 73
            |:..:::.:.| ....|.|..|:..|.||::.|.|||:.|:.|.:....|...| :|.     |:
Mouse     4 VVLMMAILLPQ-SLAHPGFFTSIGQMTDLIHNEKDLVTSLKDYIKAEEDKLEQIKKWA-----EK 62

  Fly    74 LDK-----SKKEQSF--DLFNRYSFIRHMQADWLMWKQYLDKPVIRDELNYKQMDNLRM-----P 126
            ||:     :|..:.|  ...|.:..::.:..:|    ..|:..:::| ::...:.||.:     |
Mouse    63 LDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEW----SELENLILKD-MSDGFISNLTIQRQYFP 122

  Fly   127 QELDLFDASEAIRRMQATYAMLSNDIAEGFLDGVQYTSKLSPIDCLAMGRHLMNQSRWTIAEQWI 191
            .:.|...|::|:.|:|.||.:.:|.|::|.|.|||:.|.|:..||..:|:....::.:...|.|:
Mouse   123 NDEDQVGAAKALFRLQDTYNLDTNTISKGNLPGVQHKSFLTAEDCFELGKVAYTEADYYHTELWM 187

  Fly   192 LAGIKAQDRKGPQTEMILLRGPTKAELFRTLGKVRFERRNEEGALKAYQAALKHSPHDLEIFQEY 256
                   ::...|.|...|....|..:...|....:::.:.:.||...:..|:..|       |:
Mouse   188 -------EQALTQLEEGELSTVDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDP-------EH 238

  Fly   257 Q----NLKRRVLTLSPSEPIREEPNDDIEEMELPPCCSG----------------RCEG----PR 297
            |    ||......:|..:...:..:.|..:.:..|...|                |.||    ||
Mouse   239 QRANGNLVYFEYIMSKEKDANKSASGDQSDQKTAPKKKGIAVDYLPERQKYEMLCRGEGIKMTPR 303

  Fly   298 KLNRLYCVYNCVTA-PFLRLAPIKTEILSVDPFVILLHDMVSHKEGALIRSSSKNQILPSETVN- 360
            :..||:|.|:.... |...|||.|.|.....|.:|..||::|..|..:::..:|.: |...||:
Mouse   304 RQKRLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPR-LSRATVHD 367

  Fly   361 -AANEFEIAKFRTSKSVWFDSDANEATLKLTQRLGEATGLDMKHSEPFQVINYGIGGVFESHFDT 424
             ...:...|::|.|||.|.....:....::..|:.:.||||:..:|..||.|||:||.:|.|||.
Mouse   368 PETGKLTTAQYRVSKSAWLSGYEDPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDF 432

  Fly   425 SLADE-DRFVN-GYIDRLATTLFYLNDVPQGGATHFPGLNITVFPKFGTVLMWYNLHTEGMLHVR 487
            :..|| |.|.. |..:|:||.|||::||..||||.||.:..:|:||.||.:.||||...|.....
Mouse   433 ARKDEPDAFRELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYS 497

  Fly   488 TMHTGCPVIVGSKWVVSKWIDDKGQEFRRPCLRSRLD 524
            |.|..|||:||:|||.:||:.::||||||||..|.|:
Mouse   498 TRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31524	NP_733379.2	P4Ha_N	31..157	CDD:285528	35/138 (25%)
		TPR_11	215..>259	CDD:290150	8/47 (17%)
		TPR_2	216..249	CDD:285020	5/32 (16%)
		P4Hc	340..507	CDD:214780	68/170 (40%)
P4ha1	NP_001303300.1	P4Ha_N	24..153	CDD:285528	35/138 (25%)
		TPR	205..238		5/39 (13%)
		P4Hc	345..518	CDD:214780	70/173 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820