Protein Alignment Erk7 and SLT2

DIOPT Version :10

• Sequence 1: NP_727335.1
• Gene: Erk7 / 31877
• FlyBaseID: FBgn0052703
• Length: 916
• Species: Drosophila melanogaster
• Sequence 2: NP_011895.1
• Gene: SLT2 / 856425
• SGDID: S000001072
• Length: 484
• Species: Saccharomyces cerevisiae
• Alignment Length: 516
• Identity: 156/516 - (30%)
• Similarity: 248/516 - (48%)
• Gaps: 99/516 - (19%)

  Fly    18 DQTVESIFDVRKRMGKGAYGIVWKA--TDRRTKNTVALKKVFDAFRDETDAQRTYREVIFLRAFR 80
            |.:|:..|.:.|.:|.||||||..|  .:.....|||:|||.:.|......:|:.||:..||.||
Yeast    16 DFSVDKRFQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 80

  Fly    81 CHPNIVRLVD---IFKASNNLD-FYLVFEFMESDLHNVIKRGNVLKDVHKRFVMYQLINAIKFIH 141
            .|.||..|.|   :|....::: .||..|.||.|:|.:||.|..|.|.|.:...||::..:|:||
Yeast    81 GHKNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQIIKSGQPLTDAHYQSFTYQILCGLKYIH 145

  Fly   142 SGNVIHRDLKPSNILIDSKCRLKVADFGLARTLSSRRIYDDLEQDGMLTDYVATRWYRAPEILVA 206
            |.:|:||||||.|:|:::.|:||:.||||||..|.    :.:|....||:||||||||||||:::
Yeast   146 SADVLHRDLKPGNLLVNADCQLKICDFGLARGYSE----NPVENSQFLTEYVATRWYRAPEIMLS 206

  Fly   207 SRNYTKGIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKIVTSLPNVTKLDIASIGPSFGSVLLSR 271
            .:.|||.||:|..||||.|.:..||:|:|...|||:.:|:..|.......:..||        |:
Yeast   207 YQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIG--------SK 263

  Fly   272 NIQRDRRYSLDEMMK--------NCCDDGISLVKALLVLNPHNRLTAKEAIRHPYVS-------- 320
            |:| |..:.|..:.|        |.....:.|::.:|..:|..|:|..||:.|||:|
Yeast   264 NVQ-DYIHQLGFIPKVPFVNLYPNANSQALDLLEQMLAFDPQKRITVDEALEHPYLSIWHDPADE 327

  Fly   321 -----RFQYASAEMDLHMDVVPPLKDHVRYDVDQYRNSLYELIDRETSCSNRTVSNSTPSSNRDE 380
                 :|:::...::...|    ||..|..:|..:|     |..|:.....:
Yeast   328 PVCSEKFEFSFESVNDMED----LKQMVIQEVQDFR-----LFVRQPLLEEQ------------- 370

  Fly   381 LPKPVRVTKQARTTSAKQPTTSPAERKKEPSSVEVTQSRKNIKLLGSAHKAQSKEINHMESAITQ 445
                    :|.:....:|......:::::||.|:            :.:.|.|:| |:.:...|.
Yeast   371 --------RQLQLQQQQQQQQQQQQQQQQPSDVD------------NGNAAASEE-NYPKQMATS 414

  Fly   446 VSIA-----------SAP--PAAAPPAPAATAPAVPRKSGDKSVPKCQHNNAA---VQREL 490
            .|:|           :.|  .|..||.|..:...:...:|:.:....|::|..   :::||
Yeast   415 NSVAPQQESFGIHSQNLPRHDADFPPRPQESMMEMRPATGNTADIPPQNDNGTLLDLEKEL 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Erk7	NP_727335.1	STKc_MAPK15-like	17..358	CDD:270841	132/366 (36%)
SLT2	NP_011895.1	STKc_MPK1	22..355	CDD:173750	128/349 (37%)