Protein Alignment Erk7 and SGV1

DIOPT Version :10

• Sequence 1: NP_727335.1
• Gene: Erk7 / 31877
• FlyBaseID: FBgn0052703
• Length: 916
• Species: Drosophila melanogaster
• Sequence 2: NP_015487.1
• Gene: SGV1 / 856290
• SGDID: S000006365
• Length: 657
• Species: Saccharomyces cerevisiae
• Alignment Length: 694
• Identity: 163/694 - (23%)
• Similarity: 286/694 - (41%)
• Gaps: 160/694 - (23%)

  Fly    29 KRMGKGAYGIVWKATDRRTKNTVALKKVFDAFRDETDAQRTYREVIFLRAFRCHPNIVRLVDIF- 92
            :::|:|.:|.|:|.....|:..||:||:..:...:.......||:..|:... |.||::|:::.
Yeast    64 EKLGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRLN-HKNIIKLIEMVY 127

  Fly    93 --------KASNNL--DFYLVFEFMESDLHNVIKRGNV-LKDVHKRFVMYQLINAIKFIHSGNVI 146
                    .||:||  .||::..:|.:||..|:....: |:....:.:|.|::..:.:||....:
Yeast   128 DHSPDITNAASSNLHKSFYMILPYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKFM 192

  Fly   147 HRDLKPSNILIDSKCRLKVADFGLARTLSSRRIY----DDLEQDG------MLTDYVATRWYRAP 201
            |||:|.:|||||....||:||||||      |:|    .:|:..|      ..|..|.|||||||
Yeast   193 HRDIKTANILIDHNGVLKLADFGLA------RLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAP 251

  Fly   202 EILVASRNYTKGIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKIVTSLPNVTKLDIASIGPSFGS 266
            |:::..:.||..:|:||:||:..|...:||:.||.:.::|...|...|...|:.|.|......|:
Yeast   252 ELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLGTPTEEDWAVARYLPGA 316

  Fly   267 VLLSRNIQRDRRYSLDEMMKNCCDDGISLVKALLVLNPHNRLTAKEAIRHPYVSRFQYASAEMDL 331
            .|.:.|.:...|   :...|...:.|:..:..||.|:|:.||||..|..||:.......|.::.|
Yeast   317 ELTTTNYKPTLR---ERFGKYLSETGLDFLGQLLALDPYKRLTAMSAKHHPWFKEDPLPSEKITL 378

  Fly   332 HMDVVPPLKDHVRYDVDQYRNSLYELIDRETSCSNRTVSNSTPSSNRDELPKPVRVTKQARTTSA 396
                  |.::....|:.:|:..:::           ::|...|::.|.      .:.::..:...
Yeast   379 ------PTEESHEADIKRYKEEMHQ-----------SLSQRVPTAPRG------HIVEKGESPVV 420

  Fly   397 KQPTTSPAERKKEPSSVEVTQSRKNIKLLGSAHKAQSKEIN------HMESAITQVSIASAPPAA 455
            |.....|...||:.:|  .....||:  |.....::.:|::      |:.|...:.:|   ||.|
Yeast   421 KNLGAIPRGPKKDDAS--FLPPSKNV--LAKPPPSKIRELHQNPRPYHVNSGYAKTAI---PPPA 478

  Fly   456 APPAPAATAPAVPRKSGDKSVPKCQHNNAAVQRELAAVAAAAAVARRKKSSWQSQAQSQ-----G 515
            ||.......|                ||:               :|..:.|..|.|.:.     .
Yeast   479 APAGVNRYGP----------------NNS---------------SRNNRFSGNSTAPNNSRNPVN 512

  Fly   516 KFHTEAKAHVQTAIQTQKDNIKDSPPRMIQESQSLTEAKAPI---PKNRYSNKMCQEKKYK---- 573
            :||.|...       :.|.|                  |.|:   |::||... ..|.:||
Yeast   513 RFHPETNV-------SSKYN------------------KVPLPLGPQSRYQGN-SNESRYKNSPN 551

  Fly   574 -KKHHSMSCITRDTFPSETEHRQQREERAYQRQMKRELQLKESYR-----RRIEAESE------- 625
             .::|:      ..:.::.|....|:.:.|.|| :....:.::|.     |.:..:..
Yeast   552 DSRYHN------PRYVNKPETNFNRQPQKYSRQ-ESNAPINKNYNPSNGSRNMAGDHHQGSRPSH 609

  Fly   626 ---PLKETTEQESKTIKVIEQKVCEHTEKKADESLSKDQQKDSI 666
               |:..:..|...|.|.||:|.....:::|....||:.|...|
Yeast   610 PQFPISPSQGQHQLTSKPIEKKNGSFKDERAKPDESKEFQNSDI 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Erk7	NP_727335.1	STKc_MAPK15-like	17..358	CDD:270841	103/350 (29%)
SGV1	NP_015487.1	STKc_BUR1	50..366	CDD:270849	98/311 (32%)