DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Erk7 and Mapk14

DIOPT Version :10

Sequence 1:NP_727335.1 Gene:Erk7 / 31877 FlyBaseID:FBgn0052703 Length:916 Species:Drosophila melanogaster
Sequence 2:NP_112282.2 Gene:Mapk14 / 81649 RGDID:70496 Length:360 Species:Rattus norvegicus


Alignment Length:408 Identity:133/408 - (32%)
Similarity:219/408 - (53%) Gaps:86/408 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 AQERRI---QELDQTVESIFDVRKR------MGKGAYGIVWKATDRRTKNTVALKKVFDAFRDET 64
            :|||..   |||::||   ::|.:|      :|.||||.|..|.|.:|.:.||:||:...|:...
  Rat     2 SQERPTFYRQELNKTV---WEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSII 63

  Fly    65 DAQRTYREVIFLRAFRCHPNIVRLVDIFKASNNL----DFYLVFEFMESDLHNVIKRGNVLKDVH 125
            .|:|||||:..|:..: |.|::.|:|:|..:.:|    |.|||...|.:||:|::| ...|.|.|
  Rat    64 HAKRTYRELRLLKHMK-HENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVK-CQKLTDDH 126

  Fly   126 KRFVMYQLINAIKFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTLSSRRIYDDLEQDGMLT 190
            .:|::||::..:|:|||.::|||||||||:.::..|.||:.||||||           ..|..:|
  Rat   127 VQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLAR-----------HTDDEMT 180

  Fly   191 DYVATRWYRAPEILVASRNYTKGIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKI--VTSLPNVT 253
            .||||||||||||::...:|.:.:|:|.:|||:.|::..:.||.||..:||:::|  :|..|   
  Rat   181 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTP--- 242

  Fly   254 KLDIASIGPSFGSVLLSRNIQRDRR---YSLDEMMK-NCCDD-------GISLVKALLVLNPHNR 307
                    |::   |::|....:.|   .||.:|.| |..:.       .:.|::.:|||:...|
  Rat   243 --------PAY---LINRMPSHEARNYIQSLAQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKR 296

  Fly   308 LTAKEAIRHPYVSRFQYASAEMDLHMDVVPPLKDHVRYD---------VDQYRNSLYELIDRETS 363
            :||.:|:.|.|.:::.....|         |:.|  .||         :|::::..|:       
  Rat   297 ITAAQALAHAYFAQYHDPDDE---------PVAD--PYDQSFESRDLLIDEWKSLTYD------- 343

  Fly   364 CSNRTVSNSTPSSNRDEL 381
               ..:|...|..:::|:
  Rat   344 ---EVISFVPPPLDQEEM 358

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Erk7NP_727335.1 STKc_MAPK15-like 17..358 CDD:270841 125/372 (34%)
Mapk14NP_112282.2 STKc_p38alpha 6..350 CDD:143382 128/394 (32%)

Return to query results.
Submit another query.