DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Erk7 and Mapk11

DIOPT Version :9

Sequence 1:	NP_001188568.1	Gene:	Erk7 / 31877	FlyBaseID:	FBgn0052703	Length:	916	Species:	Drosophila melanogaster
Sequence 2:	XP_017450608.1	Gene:	Mapk11 / 689314	RGDID:	1309340	Length:	371	Species:	Rattus norvegicus

Alignment Length:	335	Identity:	118/335 - (35%)
Similarity:	187/335 - (55%)	Gaps:	54/335 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 QELDQTVESIFDVRKRM------GKGAYGIVW-------KATDRRTKNTVALKKVFDAFRDETDA 66
            |||::||   ::|.:|:      |.||||.||       .|.|.|.:..||:||:...|:....|
  Rat    11 QELNKTV---WEVPQRLQGLRPVGSGAYGSVWSHPGPPHSAYDARLRQKVAVKKLSRPFQSLIHA 72

  Fly    67 QRTYREVIFLRAFRCHPNIVRLVDIFKASNNL-DF---YLVFEFMESDLHNVIKRGNVLKDVHKR 127
            :|||||:..|:..: |.|::.|:|:|..:.:: ||   |||...|.:||:|::| ...|.|.|.:
  Rat    73 RRTYRELRLLKHLK-HENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVK-CQALSDEHVQ 135

  Fly   128 FVMYQLINAIKFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTLSSRRIYDDLEQDGMLTDY 192
            |::|||:..:|:|||..:|||||||||:.::..|.|::.||||||           :.|..:|.|
  Rat   136 FLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLAR-----------QADEEMTGY 189

  Fly   193 VATRWYRAPEILVASRNYTKGIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKIVTSLPNVTKLDI 257
            |||||||||||::...:|.:.:|:|.:|||:.|:::.|.||.|...::|:::|           :
  Rat   190 VATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGNDYIDQLKRI-----------M 243

  Fly   258 ASIGPSFGSVLLSRNIQRDRRY--SLDEMMKNCCDD--------GISLVKALLVLNPHNRLTAKE 312
            ..:|.....||...:.:..|.|  ||..|.:.....        .:.|:..:|||:...|::|.|
  Rat   244 EVVGTPSPEVLAKISSEHARTYIQSLPPMPQKDLSSVFHGANPLAVDLLGRMLVLDSDQRVSAAE 308

  Fly   313 AIRHPYVSRF 322
            |:.|.|.|::
  Rat   309 ALAHAYFSQY 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Erk7	NP_001188568.1	STKc_MAPK15-like	17..358	CDD:270841	116/333 (35%)
Mapk11	XP_017450608.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0660
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D324618at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820