Protein Alignment Erk7 and Mapk12

DIOPT Version :10

• Sequence 1: NP_727335.1
• Gene: Erk7 / 31877
• FlyBaseID: FBgn0052703
• Length: 916
• Species: Drosophila melanogaster
• Sequence 2: NP_068514.1
• Gene: Mapk12 / 60352
• RGDID: 70975
• Length: 367
• Species: Rattus norvegicus
• Alignment Length: 334
• Identity: 116/334 - (34%)
• Similarity: 179/334 - (53%)
• Gaps: 67/334 - (20%)

  Fly    15 QELDQT---VESIFDVRKRMGKGAYGIVWKATDRRTKNTVALKKVFDAFRDETDAQRTYREVIFL 76
            ||:.:|   |.:::...:.:|.||||.|..|.|.||.|.||:||::..|:.|..|:|.|||:..|
  Rat    14 QEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAVDSRTGNKVAIKKLYRPFQSELFAKRAYRELRLL 78

  Fly    77 RAFRCHPNIVRLVDIFKASNNL----DFYLVFEFMESDLHNVIKRGNVLKDVHKRFVMYQLINAI 137
            :..| |.|::.|:|:|.....|    |||||..||.:||..::|...:.:| ..:|::||::..:
  Rat    79 KHMR-HENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHETLSED-RIQFLVYQMLKGL 141

  Fly   138 KFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTLSSRRIYDDLEQDGMLTDYVATRWYRAPE 202
            |:||:..||||||||.|:.::..|.||:.||||||           :.|..:|.||.||||||||
  Rat   142 KYIHAAGVIHRDLKPGNLAVNEDCELKILDFGLAR-----------QADSEMTGYVVTRWYRAPE 195

  Fly   203 ILVASRNYTKGIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKI---------------------- 245
            :::....||:.:|:|.:|||:.|||..|.||:|...::|:::|
  Rat   196 VILNWMRYTQTVDIWSVGCIMAEMITGKILFKGNDHLDQLKEIMKVTGTPPPEFVQKLQSAEAKN 260

  Fly   246 -VTSLPNVTKLDIASIGPSFGSVLLSRNIQRDRRYSLDEMMKNCCDDGISLVKALLVLNPHNRLT 309
             :..||.:.|.|.||:                        :.|.....::|::.:|||:...|:|
  Rat   261 YMEGLPELEKKDFASV------------------------LTNASPQAVNLLEKMLVLDAEQRVT 301

  Fly   310 AKEAIRHPY 318
            |.||:.|||
  Rat   302 AAEALAHPY 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Erk7	NP_727335.1	STKc_MAPK15-like	17..358	CDD:270841	114/332 (34%)
Mapk12	NP_068514.1	STKc_p38gamma	11..353	CDD:143385	116/334 (35%)
		TXY	183..185		1/1 (100%)