Protein Alignment Erk7 and mapk6

DIOPT Version :9

• Sequence 1: NP_001188568.1
• Gene: Erk7 / 31877
• FlyBaseID: FBgn0052703
• Length: 916
• Species: Drosophila melanogaster
• Sequence 2: NP_001039017.1
• Gene: mapk6 / 565830
• ZFINID: ZDB-GENE-050420-7
• Length: 729
• Species: Danio rerio
• Alignment Length: 698
• Identity: 173/698 - (24%)
• Similarity: 302/698 - (43%)
• Gaps: 145/698 - (20%)

  Fly    29 KRMGKGAYGIVWKATDRRTKNTVALKKVFDAFRDETDAQRTYREVIFLRAFRCHPNIVRLV---- 89
            |.:|.|..|:|:.|.|......||:||:  ...|....:...||:..:|... |.|||::.
Zfish    24 KPLGYGGNGLVFSAVDTDCDKRVAVKKI--VLTDPQSVKHALREIKIIRRLD-HDNIVKVFETLG 85

  Fly    90 --------DIFKASNNLDFYLVFEFMESDLHNVIKRGNVLKDVHKRFVMYQLINAIKFIHSGNVI 146
                    |:...:.....|:|.|:||:||..|:::| :|.:.|.|..||||:..:|:|||.||:
Zfish    86 PSGRRLTEDVSSLTEVNSVYIVQEYMETDLCKVLEQG-LLSEDHARLFMYQLLRGLKYIHSANVL 149

  Fly   147 HRDLKPSNILIDSK-CRLKVADFGLARTLSSRRIYDDLEQDGMLTDYVATRWYRAPEILVASRNY 210
            ||||||:|:.:::: ..||:.||||||.:...     ....|.|::.:.|:|||:|.:|::..||
Zfish   150 HRDLKPANLFVNTEDLVLKIGDFGLARIMDPH-----YSHKGHLSEGLVTKWYRSPRLLLSPNNY 209

  Fly   211 TKGIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKIVTSLPNV---TKLDIASIGPSFGSVLLSRN 272
            ||.||||..|||..||:..|.||.|...:.|::.|:.|:|.|   .:|::.|:.|.|     .:|
Zfish   210 TKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILESIPVVHEEDRLELQSVIPVF-----IKN 269

  Fly   273 IQRDRRYSLDEMMKNCCDDGISLVKALLVLNPHNRLTAKEAIRHPYVSRFQYASAE-MDLHM--- 333
            ...:....|.:::.....:.:..::.:|..||.:||||:||:.|||:|.:.:...| :.||.
Zfish   270 DMSEPHTPLAKLLPGVSPEALDFLEKILTFNPMDRLTAEEALAHPYMSDYSFPLDEPVSLHPFHI 334

  Fly   334 -----DVVPPLKD----HV----RY------DVDQYRNSLYELIDRETSCSNRTVSNSTPSSNRD 379
                 |::  |.|    ||    ||      |.|.:.:|.:||.|.:.  ..|.:|:.|     |
Zfish   335 EDEVDDIL--LMDESHSHVYNWDRYHESQFSDQDWHLHSTHELEDVQR--DPRAMSDVT-----D 390

  Fly   380 ELPKPVRVTKQARTTSAKQPTTSPAERKKEPS---------SVEVTQSRK----------NIKLL 425
            |        ::.:....|.......:..::||         .:|.....|          |.|.:
Zfish   391 E--------EEVQIDPRKYMDGDCEKFLEDPSFDLPPEHLWQLEDHHENKYCDQECSYTCNYKAV 447

  Fly   426 GSAHKA----QSKEINHMESAITQVSIASAPPAAAPPAPAATAPAVPRKSGDKSVPKCQHNNAAV 486
            ..::..    :..|:||.......:.:::.....:           ..|...|...||: .|..|
Zfish   448 SPSYLDNLIWRDSEVNHYYEPKLIIDLSNWKEQQS-----------KEKIDKKGKSKCE-KNGLV 500

  Fly   487 QRELAAVAAAA--AVARRKKSSWQSQAQSQG-KFHTEAKAHVQTAIQTQKDNIKDSPPRMIQE-S 547
            :.::|...|:.  .|..:.:...:.|..:|| .|.:...:.::.::|.:..::.     ::.| :
Zfish   501 KAQIALKEASQNHTVPEKDRDQEKHQNHNQGFDFDSFIASTIKLSLQPESGDVD-----LLNELN 560

  Fly   548 QSLTEAKAPIPKNRYSNKMCQEKKYKKKHHSMSCITRDTFPSET--------------------- 591
            .|:::.....|....|..:.|||:.|...:......|...|.|:
Zfish   561 TSVSQLDTRAPCGSMSKSISQEKEEKCLVNLAQLGVRAPCPWESFTDCGVAESSLIDQACWDVRK 625

  Fly   592 EHRQQREERAYQRQMKRELQLKESYRRRIEAESEPLK-----ETTEQE 634
            :.:.|:|..:.|..     .|...:.:|.:.|.|.|:     .|||.:
Zfish   626 DEQLQKENSSCQSS-----YLDRLFNKRDDVEPEILEPVEVVSTTESD 668

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Erk7	NP_001188568.1	STKc_MAPK15-like	17..358	CDD:270841	120/367 (33%)
mapk6	NP_001039017.1	STKc_MAPK4_6	14..355	CDD:143359	114/346 (33%)
		S_TKc	20..316	CDD:214567	104/305 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0660
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D741207at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910