Protein Alignment Erk7 and MAPK13

DIOPT Version :9

• Sequence 1: NP_001188568.1
• Gene: Erk7 / 31877
• FlyBaseID: FBgn0052703
• Length: 916
• Species: Drosophila melanogaster
• Sequence 2: NP_002745.1
• Gene: MAPK13 / 5603
• HGNCID: 6875
• Length: 365
• Species: Homo sapiens
• Alignment Length: 376
• Identity: 119/376 - (31%)
• Similarity: 201/376 - (53%)
• Gaps: 51/376 - (13%)

  Fly    16 ELDQTVESIFDVRKRMGKGAYGIVWKATDRRTKNTVALKKVFDAFRDETDAQRTYREVIFLRAFR 80
            ||.:|..|    ...:|.||||.|..|.|:|:...||:||:...|:.|..|:|.|||::.|:..:
Human    20 ELPKTYVS----PTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQ 80

  Fly    81 CHPNIVRLVDIFKASNNL----DFYLVFEFMESDLHNVIKRGNVLKDVHKRFVMYQLINAIKFIH 141
             |.|::.|:|:|..:::|    |||||..||::||..::  |....:...::::||::..:|:||
Human    81 -HENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIM--GMEFSEEKIQYLVYQMLKGLKYIH 142

  Fly   142 SGNVIHRDLKPSNILIDSKCRLKVADFGLARTLSSRRIYDDLEQDGMLTDYVATRWYRAPEILVA 206
            |..|:||||||.|:.::..|.||:.||||||           ..|..:|.||.||||||||::::
Human   143 SAGVVHRDLKPGNLAVNEDCELKILDFGLAR-----------HADAEMTGYVVTRWYRAPEVILS 196

  Fly   207 SRNYTKGIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKI--VTSLPN---VTKLDIASIGPSFGS 266
            ..:|.:.:|:|.:|||:.||:..|.||:|...::|:.:|  ||.:|.   |.||: .....|:
Human   197 WMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLN-DKAAKSY-- 258

  Fly   267 VLLSRNIQRDRRYSLDEMMKNCCDDGISLVKALLVLNPHNRLTAKEAIRHPYVSRFQYASAEMDL 331
               .:::.:..|....::..........|::.:|.|:...||||.:|:.||:...|:....|.:.
Human   259 ---IQSLPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEEETEA 320

  Fly   332 HMDVVPPLKD---HVRYDVDQYRNSLYELIDRETSCSNRTVSNSTPSSNRD 379
            ..    |..|   |.:..||:::..:|           :.:.|.:|.:.:|
Human   321 QQ----PFDDSLEHEKLTVDEWKQHIY-----------KEIVNFSPIARKD 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Erk7	NP_001188568.1	STKc_MAPK15-like	17..358	CDD:270841	115/352 (33%)
MAPK13	NP_002745.1	STKc_p38delta	9..351	CDD:143384	117/369 (32%)
		TXY	180..182		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0660
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D324618at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820