Protein Alignment Erk7 and MAPK9

DIOPT Version :9

• Sequence 1: NP_001188568.1
• Gene: Erk7 / 31877
• FlyBaseID: FBgn0052703
• Length: 916
• Species: Drosophila melanogaster
• Sequence 2: NP_001351537.1
• Gene: MAPK9 / 5601
• HGNCID: 6886
• Length: 424
• Species: Homo sapiens
• Alignment Length: 435
• Identity: 139/435 - (31%)
• Similarity: 222/435 - (51%)
• Gaps: 75/435 - (17%)

  Fly    19 QTVESIFDVRKR------MGKGAYGIVWKATDRRTKNTVALKKVFDAFRDETDAQRTYREVIFLR 77
            |..:|.|.|.||      :|.||.|||..|.|......||:||:...|:::|.|:|.|||::.|:
Human    14 QVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLK 78

  Fly    78 AFRCHPNIVRLVDIFKASNNL----DFYLVFEFMESDLHNVIKRGNVLKDVHKR--FVMYQLINA 136
            ... |.||:.|:::|.....|    |.|||.|.|:::|..||.    ::..|:|  :::||::..
Human    79 CVN-HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH----MELDHERMSYLLYQMLCG 138

  Fly   137 IKFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTLSSRRIYDDLEQDGMLTDYVATRWYRAP 201
            ||.:||..:||||||||||::.|.|.||:.|||||||..:         :.|:|.||.||:||||
Human   139 IKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACT---------NFMMTPYVVTRYYRAP 194

  Fly   202 EILVASRNYTKGIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKIVTSLPNVTKLDIASIGPSFGS 266
            |::: ...|.:.:|:|.:|||:||:::...:||||..::|..|::..|...:...:..:.|:.
Human   195 EVIL-GMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQPTV-- 256

  Fly   267 VLLSRNIQRDR-RY---------------SLDEMMKNCCDDGISLVKALLVLNPHNRLTAKEAIR 315
                ||...:| :|               |..|..|........|:..:||::|..|::..||:|
Human   257 ----RNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDEALR 317

  Fly   316 HPYVSRFQYASAEMDLHMDVVPPLK------DHVRYDVDQYRNSLY-ELIDRETSCSNRTV---- 369
            |||::.: |..||.:     .||.:      :...:.:::::..:| |::|.|....|..|
Human   318 HPYITVW-YDPAEAE-----APPPQIYDAQLEEREHAIEEWKELIYKEVMDWEERSKNGVVKDQP 376

  Fly   370 ------SNSTP---SSNRDELPKPVRVTKQARTTSAKQPTTSPAE 405
                  ||:||   ||..|........|..:.|.|:...:|.|.|
Human   377 SDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPLE 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Erk7	NP_001188568.1	STKc_MAPK15-like	17..358	CDD:270841	122/373 (33%)
MAPK9	NP_001351537.1	STKc_JNK	25..360	CDD:270840	116/361 (32%)
		TXY	183..185		1/1 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	368..424		15/54 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D741207at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920