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Protein Alignment Erk7 and MAPK11

DIOPT Version :9

Sequence 1:	NP_001188568.1	Gene:	Erk7 / 31877	FlyBaseID:	FBgn0052703	Length:	916	Species:	Drosophila melanogaster
Sequence 2:	NP_002742.3	Gene:	MAPK11 / 5600	HGNCID:	6873	Length:	364	Species:	Homo sapiens

Alignment Length:	423	Identity:	129/423 - (30%)
Similarity:	207/423 - (48%)	Gaps:	89/423 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 QELDQTVESIFDVRKRM------GKGAYGIVWKATDRRTKNTVALKKVFDAFRDETDAQRTYREV 73
            |||::||   ::|.:|:      |.||||.|..|.|.|.:..||:||:...|:....|:|||||:
Human    11 QELNKTV---WEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYREL 72

  Fly    74 IFLRAFRCHPNIVRLVDIFKASNNL-DF---YLVFEFMESDLHNVIKRGNVLKDVHKRFVMYQLI 134
            ..|:..: |.|::.|:|:|..:.:: ||   |||...|.:||:|::| ...|.|.|.:|::|||:
Human    73 RLLKHLK-HENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVK-CQALSDEHVQFLVYQLL 135

  Fly   135 NAIKFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTLSSRRIYDDLEQDGMLTDYVATRWYR 199
            ..:|:|||..:|||||||||:.::..|.|::.||||||           :.|..:|.||||||||
Human   136 RGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLAR-----------QADEEMTGYVATRWYR 189

  Fly   200 APEILVASRNYTKGIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKIVTSLPNVTKLDIASIGPSF 264
            ||||::...:|.:.:|:|.:|||:.|:::.|.||.|:..::|:::|           :..:|...
Human   190 APEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRI-----------MEVVGTPS 243

  Fly   265 GSVLLSRNIQRDRRY----------SLDEMMKNCCDDGISLVKALLVLNPHNRLTAKEAIRHPYV 319
            ..||...:.:..|.|          .|..:.:......|.|:..:|||:...|::|.||:.|.|.
Human   244 PEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYF 308

  Fly   320 SRFQYASAEMDLHMDVVPPLKDHVRYDVDQYRNSLYELIDRETSCSNRTVSNSTPSSNRDELPKP 384
            |::.....|.:.                        |..|.......||:......:.::.|
Human   309 SQYHDPEDEPEA------------------------EPYDESVEAKERTLEEWKELTYQEVL--- 346

  Fly   385 VRVTKQARTTSAKQPTTSPAERKKEPSSVEVTQ 417
                           :..|.|..|.|.|:|:.|
Human   347 ---------------SFKPPEPPKPPGSLEIEQ 364

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.