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Protein Alignment Erk7 and MAPK1

DIOPT Version :9

Sequence 1:	NP_001188568.1	Gene:	Erk7 / 31877	FlyBaseID:	FBgn0052703	Length:	916	Species:	Drosophila melanogaster
Sequence 2:	NP_002736.3	Gene:	MAPK1 / 5594	HGNCID:	6871	Length:	360	Species:	Homo sapiens

Alignment Length:	361	Identity:	131/361 - (36%)
Similarity:	200/361 - (55%)	Gaps:	47/361 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 IFDVRKR------MGKGAYGIVWKATDRRTKNTVALKKVFDAFRDETDAQRTYREVIFLRAFRCH 82
            :|||..|      :|:||||:|..|.|...|..||:||: ..|..:|..|||.||:..|..|| |
Human    18 VFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKI-SPFEHQTYCQRTLREIKILLRFR-H 80

  Fly    83 PNIVRLVDIFKA---SNNLDFYLVFEFMESDLHNVIKRGNVLKDVHKRFVMYQLINAIKFIHSGN 144
            .||:.:.||.:|   ....|.|:|.:.||:||:.::|..::..| |..:.:||::..:|:|||.|
Human    81 ENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSND-HICYFLYQILRGLKYIHSAN 144

  Fly   145 VIHRDLKPSNILIDSKCRLKVADFGLARTLSSRRIYDDLEQDGMLTDYVATRWYRAPEILVASRN 209
            |:||||||||:|:::.|.||:.||||||...     .|.:..|.||:||||||||||||::.|:.
Human   145 VLHRDLKPSNLLLNTTCDLKICDFGLARVAD-----PDHDHTGFLTEYVATRWYRAPEIMLNSKG 204

  Fly   210 YTKGIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKIVTSLPNVTKLDIASIGPSFGSVLLSRN-- 272
            |||.||:|.:||||.||:..:|:|.|...::|:..|:..|.:.::.|:..|     ..|.:||
Human   205 YTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCI-----INLKARNYL 264

  Fly   273 --IQRDRRYSLDEMMKNCCDDGISLVKALLVLNPHNRLTAKEAIRHPYVSRFQYASAE------- 328
              :....:...:.:..|.....:.|:..:|..|||.|:..::|:.|||:.::...|.|
Human   265 LSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPF 329

  Fly   329 -MDLHMDVVPPLKDHVRYDVDQYRNSLYELIDRETS 363
             .|:.:|.:|             :..|.|||..||:
Human   330 KFDMELDDLP-------------KEKLKELIFEETA 352

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.