DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Erk7 and Mapk3

DIOPT Version :9

Sequence 1:	NP_001188568.1	Gene:	Erk7 / 31877	FlyBaseID:	FBgn0052703	Length:	916	Species:	Drosophila melanogaster
Sequence 2:	XP_038944453.1	Gene:	Mapk3 / 50689	RGDID:	3046	Length:	406	Species:	Rattus norvegicus

Alignment Length:	394	Identity:	135/394 - (34%)
Similarity:	202/394 - (51%)	Gaps:	89/394 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 FDVRKR------MGKGAYGIVWKATDRRTKNTVALKKVFDAFRDETDAQRTYREVIFLRAFRCHP 83
            |||..|      :|:||||:|..|.|...|..||:||: ..|..:|..|||.||:..|..|| |.
  Rat    37 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKI-SPFEHQTYCQRTLREIQILLRFR-HE 99

  Fly    84 NIVRLVDIFKASN---NLDFYLVFEFMESDLHNVIKRGNVLKDVHKRFVMYQLINAIKFIHSGNV 145
            |::.:.||.:|..   ..|.|:|.:.||:||:.::|...:..| |..:.:||::..:|:|||.||
  Rat   100 NVIGIRDILRAPTLEAMRDVYIVQDLMETDLYKLLKSQQLSND-HICYFLYQILRGLKYIHSANV 163

  Fly   146 IHRDLKPSNILIDSKCRLKVADFGLARTLSSRRIYDDLEQD--GMLTDYVATRWYRAPEILVASR 208
            :||||||||:||::.|.||:.||||||..       |.|.|  |.||:||||||||||||::.|:
  Rat   164 LHRDLKPSNLLINTTCDLKICDFGLARIA-------DPEHDHTGFLTEYVATRWYRAPEIMLNSK 221

  Fly   209 NYTKGIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKI-----------------------VTSLP 250
            .|||.||:|.:||||.||:..:|:|.|...::|:..|                       :.|||
  Rat   222 GYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLP 286

  Fly   251 NVTKLDIASIGPSFGSVLLSRNIQRDRRYSLDEMMKNCCDDGISLVKALLVLNPHNRLTAKEAIR 315
            :.||:..|.:.|...|                        ..:.|:..:|..||:.|:|.:||:.
  Rat   287 SKTKVAWAKLFPKSDS------------------------KALDLLDRMLTFNPNKRITVEEALA 327

  Fly   316 HPYVSRFQYASAEMD--------LHMDVVPPL----------KDHVRYDV---DQYRNSLYELID 359
            |||:.::...:.|:.        :.:..|.|:          ::...:|:   |..:..|.|||.
  Rat   328 HPYLEQYYDPTDEVSRPPAAGRGISVPSVRPVPYCLCPQPVAEEPFTFDMELDDLPKERLKELIF 392

  Fly   360 RETS 363
            :||:
  Rat   393 QETA 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Erk7	NP_001188568.1	STKc_MAPK15-like	17..358	CDD:270841	131/387 (34%)
Mapk3	XP_038944453.1	STKc_ERK1_2_like	37..397	CDD:270839	135/394 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D741207at2759
OrthoFinder	1	1.000	-	-		FOG0000164
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920