Protein Alignment Erk7 and Mapk12

DIOPT Version :10

• Sequence 1: NP_727335.1
• Gene: Erk7 / 31877
• FlyBaseID: FBgn0052703
• Length: 916
• Species: Drosophila melanogaster
• Sequence 2: XP_006521121.1
• Gene: Mapk12 / 29857
• MGIID: 1353438
• Length: 390
• Species: Mus musculus
• Alignment Length: 333
• Identity: 122/333 - (36%)
• Similarity: 189/333 - (56%)
• Gaps: 42/333 - (12%)

  Fly    15 QELDQT---VESIFDVRKRMGKGAYGIVWKATDRRTKNTVALKKVFDAFRDETDAQRTYREVIFL 76
            ||:.:|   |.:::...:.:|.||||.|..|.|.||.|.||:||::..|:.|..|:|.|||:..|
Mouse    14 QEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAVDSRTGNKVAIKKLYRPFQSELFAKRAYRELRLL 78

  Fly    77 RAFRCHPNIVRLVDIFKASNNL----DFYLVFEFMESDLHNVIKRGNVLKDVHKRFVMYQLINAI 137
            :..| |.|::.|:|:|....:|    |||||..||.:||..::|...:.:| ..:|::||::..:
Mouse    79 KHMR-HENVIGLLDVFTPDESLDDFTDFYLVMPFMGTDLGKLMKHETLSED-RIQFLVYQMLKGL 141

  Fly   138 KFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTLSSRRIYDDLEQDGMLTDYVATRWYRAPE 202
            |:||:..||||||||.|:.::..|.||:.||||||           :.|..:|.||.||||||||
Mouse   142 KYIHAAGVIHRDLKPGNLAVNEDCELKILDFGLAR-----------QADSEMTGYVVTRWYRAPE 195

  Fly   203 ILVASRNYTKGIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKI--VTSLPN---VTKLDIASI-- 260
            :::....||:.:|:|.:|||:.|||..|.||:|...::|:::|  :|..|.   |.||..|.:
Mouse   196 VILNWMRYTQTVDIWSVGCIMAEMITGKILFKGNDHLDQLKEIMKITGTPPPEFVQKLQSAEVSG 260

  Fly   261 -----GPSFGS--VLLSRNIQRDRRYSLDEMMK--------NCCDDGISLVKALLVLNPHNRLTA 310
                 |...|.  :.|..:..::....|.|:.|        |.....::|::.:|||:...|:||
Mouse   261 SGWWAGLGLGGWPITLFPSQAKNYMEGLPELEKKDFASVLTNASPQAVNLLERMLVLDAEQRVTA 325

  Fly   311 KEAIRHPY 318
            .||:.|||
Mouse   326 AEALTHPY 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Erk7	NP_727335.1	STKc_MAPK15-like	17..358	CDD:270841	120/331 (36%)
Mapk12	XP_006521121.1	STKc_p38gamma	11..376	CDD:143385	122/333 (37%)