back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Erk7 and Mapk11

DIOPT Version :9

Sequence 1:	NP_001188568.1	Gene:	Erk7 / 31877	FlyBaseID:	FBgn0052703	Length:	916	Species:	Drosophila melanogaster
Sequence 2:	NP_035291.4	Gene:	Mapk11 / 19094	MGIID:	1338024	Length:	364	Species:	Mus musculus

Alignment Length:	328	Identity:	118/328 - (35%)
Similarity:	186/328 - (56%)	Gaps:	47/328 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 QELDQTVESIFDVRKRM------GKGAYGIVWKATDRRTKNTVALKKVFDAFRDETDAQRTYREV 73
            |||::||   ::|.:|:      |.||||.|..|.|.|.:..||:||:...|:....|:|||||:
Mouse    11 QELNKTV---WEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYREL 72

  Fly    74 IFLRAFRCHPNIVRLVDIFKASNNL-DF---YLVFEFMESDLHNVIKRGNVLKDVHKRFVMYQLI 134
            ..|:..: |.|::.|:|:|..:.:: ||   |||...|.:||:|::| ...|.|.|.:|::|||:
Mouse    73 RLLKHLK-HENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVK-CQALSDEHVQFLVYQLL 135

  Fly   135 NAIKFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTLSSRRIYDDLEQDGMLTDYVATRWYR 199
            ..:|:|||..:|||||||||:.::..|.|::.||||||           :.|..:|.||||||||
Mouse   136 RGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLAR-----------QADEEMTGYVATRWYR 189

  Fly   200 APEILVASRNYTKGIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKIVTSLPNVTKLDIASIGPSF 264
            ||||::...:|.:.:|:|.:|||:.|:::.|.||.|...::|:::|           :..:|...
Mouse   190 APEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGNDYIDQLKRI-----------MEVVGTPS 243

  Fly   265 GSVLLSRNIQRDRRY--SLDEMMKNCCDD--------GISLVKALLVLNPHNRLTAKEAIRHPYV 319
            ..||...:.:..|.|  ||..|.:.....        .|.|:..:|||:...|::|.||:.|.|.
Mouse   244 PEVLAKISSEHARTYIQSLPPMPQKDLSSVFHGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYF 308

  Fly   320 SRF 322
            |::
Mouse   309 SQY 311

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.