Protein Alignment Erk7 and kgb-1

DIOPT Version :10

• Sequence 1: NP_727335.1
• Gene: Erk7 / 31877
• FlyBaseID: FBgn0052703
• Length: 916
• Species: Drosophila melanogaster
• Sequence 2: NP_499922.1
• Gene: kgb-1 / 176866
• WormBaseID: WBGene00002187
• Length: 390
• Species: Caenorhabditis elegans
• Alignment Length: 384
• Identity: 124/384 - (32%)
• Similarity: 192/384 - (50%)
• Gaps: 56/384 - (14%)

  Fly     4 YQTAHAQERRIQELDQTVESIFDVRKR------MGKGAYGIVWKATDRRTKNTVALKKVFDAFRD 62
            |..:...:..|::.....:|.|.:..|      :..||.|.|..|.|..|...||:||:...|..
 Worm    11 YDASRFHQVTIRDPIAGADSTFTIPTRYVNLSFLNAGAQGTVVMADDLVTTQRVAIKKMQQPFVM 75

  Fly    63 ETDAQRTYREVIFLRAFRCHPNIVRLVDIFKASNNL----DFYLVFEFMESDLHNVIKRGNVLKD 123
            ...|:|.|||.|.|...: ||||:||::.|....:|    :.|||.|.|..:||.||.|   |:.
 Worm    76 TMSAKRAYREFILLTTIK-HPNIIRLLNAFTPDTSLSTFREVYLVMELMTHNLHEVIHR---LRL 136

  Fly   124 VHK--RFVMYQLINAIKFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTLSSRRIYDDLEQD 186
            .||  .|.:||.:.|||.:|:..|||||||||||:::.:|.|||.||||||.       .:::..
 Worm   137 DHKTLSFFVYQSLCAIKHLHNSGVIHRDLKPSNIVVNDRCVLKVLDFGLARK-------KNVDTS 194

  Fly   187 GMLTDYVATRWYRAPEILVASRNYTKGIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKIVTSLPN 251
            ..::|||.||:|||||::: ...|::.:|:|.:|||..|||....||.|...::|..||.:.|..
 Worm   195 MRMSDYVVTRYYRAPEVIL-GLPYSEKVDIWSVGCIFAEMINHTVLFPGKDRIDQWTKIYSVLGT 258

  Fly   252 VTKLDIASIGPSFGSVLLSRNIQRDRRYSLDEMMKNCCDDGI-----------------SLVKAL 299
            .....|:.:|.|  :.:..|::.|.:..:..|::.   |...                 .|:..:
 Worm   259 PDDHFISQLGQS--AAMYVRSLPRHQARAFSEIVP---DTNFLPETENPRVHLTPHVARDLLFNM 318

  Fly   300 LVLNPHNRLTAKEAIRHPYVSRFQYASAEMDLHMDVVPPLKDHVRYD--VDQYRNSLYE 356
            |.:||..|.:.::|:.|||| :..:...|::      .|..:: |||  :|....:|.|
 Worm   319 LKINPEERYSVEDALNHPYV-KLWFKDDEVN------APASEN-RYDQEIDFADKTLIE 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Erk7	NP_727335.1	STKc_MAPK15-like	17..358	CDD:270841	122/371 (33%)
kgb-1	NP_499922.1	Protein Kinases, catalytic domain	37..378	CDD:473864	120/358 (34%)