Protein Alignment Erk7 and mapk6

DIOPT Version :9

• Sequence 1: NP_001188568.1
• Gene: Erk7 / 31877
• FlyBaseID: FBgn0052703
• Length: 916
• Species: Drosophila melanogaster
• Sequence 2: XP_002936385.1
• Gene: mapk6 / 100494114
• XenbaseID: XB-GENE-478419
• Length: 720
• Species: Xenopus tropicalis
• Alignment Length: 689
• Identity: 161/689 - (23%)
• Similarity: 299/689 - (43%)
• Gaps: 137/689 - (19%)

  Fly    25 FDVRKR------MGKGAYGIVWKATDRRTKNTVALKKVFDAFRDETDAQRTYREVIFLRAFRCHP 83
            ||:..|      :|.|..|:|:.|.|......||:||:  ...|....:...||:..:|... |.
 Frog    14 FDLGSRYMDLKPLGYGGNGLVFSAVDNDCDKRVAVKKI--VLTDPQSVKHALREIKIIRRLD-HD 75

  Fly    84 NIVR-----------LVDIFKASNNLD-FYLVFEFMESDLHNVIKRGNVLKDVHKRFVMYQLINA 136
            |||:           |.|...:...|: .|:|.::||:||..::::| .|::.|.|..||||:..
 Frog    76 NIVKVFEILGPNGRQLTDDVSSLTELNCVYIVQDYMETDLAKLLEQG-PLREEHARLFMYQLLRG 139

  Fly   137 IKFIHSGNVIHRDLKPSNILIDSK-CRLKVADFGLARTLSSRRIYDDLEQDGMLTDYVATRWYRA 200
            :|:|||.||:||||||:|:.|::: ..:|:.||||||.:...     ....|.|::.:.|:|||:
 Frog   140 LKYIHSANVLHRDLKPANLFINTEDLVVKIGDFGLARIMDPH-----YSHKGHLSEGLVTKWYRS 199

  Fly   201 PEILVASRNYTKGIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKIVTSLPNVTKLD---IASIGP 262
            |.:|::..||||.||||..|||..||:..|.||.|...:.|::.|:.|:|.|.:.|   :.::.|
 Frog   200 PRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILESIPVVHEEDRQELLNVIP 264

  Fly   263 SFGSVLLSRNIQRDRRYSLDEMMKNCCDDGISLVKALLVLNPHNRLTAKEAIRHPYVSRFQYASA 327
            .:     .:|...:....|.:::.....:.:..::.:|..:|.:||||:||:.|||:|.:.:...
 Frog   265 VY-----IKNDMSEPHKPLTQLLPGISSEALDFLEQILTFSPMDRLTAEEALSHPYMSIYSFPMD 324

  Fly   328 E--------MDLHMDVVPPLKD-HVR-YDVDQYRNSLYELIDRETSCSN-----------RTVSN 371
            |        ::..:|.:..:.| |.: |:.::|..|  :..|.:....|           |.:|:
 Frog   325 EPISSHPFHIEDEVDDILLMDDSHSQVYNWERYHES--DFSDHDWPIHNNFEVDEVQRDPRALSD 387

  Fly   372 STPSSNRDELPKPVRVTKQARTTSAKQP------TTSPA-----ERKKEPSSVEVTQSRKNIKLL 425
            .  |.:.:....|.:.....|....:.|      :|.|.     ..:.:...:|.:.: .|.|:.
 Frog   388 G--SDDEEVQVDPRKYLDGDREKYLEDPAFDPHFSTEPCWQYLDHHENKYCDLECSHT-CNYKMR 449

  Fly   426 GSAHKA----QSKEINHMESAITQVSIASAPPAAAPPAPAATAPAVPRKSGDKSVPKCQHNNAAV 486
            .|::..    :..|:||.......:.:::            .......|:..|...||: .|..|
 Frog   450 SSSYLDNLVWKESEVNHYYEPKLIIDLSN------------WKEQNKEKADKKGKSKCE-RNGLV 501

  Fly   487 QRELAAVAAAAAVARRKKSSWQSQAQSQGKFHTEAKAHVQTAIQTQK---DNIKDSPPRMIQESQ 548
            :.:||...|:..:..:::     :...:..|.:.....::.::|...   |.:.|.       :.
 Frog   502 KAQLALAEASQQLVEKER-----EKHKEFDFDSFIAGTIELSLQHDSSCVDKLNDL-------NS 554

  Fly   549 SLTEAKAPIPKNRYSNKMCQEKKYK----------KKHHSM--------SCITRDTFPSETEHRQ 595
            |:|:.:.   ||..|..:..||:.|          :..:|.        .|..:|.|..:.
 Frog   555 SVTQLEL---KNLISKSVSMEKQEKGMANLAQLGARNQNSWDSQIVSGEDCFLKDQFCCDV---- 612

  Fly   596 QREERAYQRQMKRELQLKESYRRRIEAESEPLKETTEQE 634
             |::...:::......|.:.:.::.|.      |.||.|
 Frog   613 -RKDDHVEKETSYTSYLDDFFSKKEET------EVTETE 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Erk7	NP_001188568.1	STKc_MAPK15-like	17..358	CDD:270841	112/364 (31%)
mapk6	XP_002936385.1	STKc_MAPK4_6	14..355	CDD:143359	110/354 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D741207at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010