Protein Alignment CG31473 and PNPO

DIOPT Version :10

• Sequence 1: NP_731188.1
• Gene: CG31473 / 318753
• FlyBaseID: FBgn0051473
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_060599.1
• Gene: PNPO / 55163
• HGNCID: 30260
• Length: 261
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 78/279 - (27%)
• Similarity: 114/279 - (40%)
• Gaps: 61/279 - (21%)

  Fly    12 TLWSAG---SLGRFAQHMSNAAH-------------QVSCIGSEEQRVYEEPHVI-------FQN 53
            |.|..|   :.||.|:.....:|             :.|..|..|  .:||.|:.       |..
Human     2 TCWLRGVTATFGRPAEWPGYLSHLCGRSAAMDLGPMRKSYRGDRE--AFEETHLTSLDPVKQFAA 64

  Fly    54 WLMAAQKEAPQV-RPRLACMATVDKSGEPVTRLTSIEEVNSHGITFFTTLGSRQAGEISANPHVS 117
            |...| .:.|.: .....|:||..:.|:|..|:..::.....|..|||...||:..|:.:||..|
Human    65 WFEEA-VQCPDIGEANAMCLATCTRDGKPSARMLLLKGFGKDGFRFFTNFESRKGKELDSNPFAS 128

  Fly   118 LHFNWAPLMRSVRIAGSAHQLTEEQVRDQFRRFPRHVQMSITHGPRYAAAEWQSR----SGFFAR 178
            |.|.|.||.|.||:.|...:|.||:....|...|:..|:.       |....||.    ..:..:
Human   129 LVFYWEPLNRQVRVEGPVKKLPEEEAECYFHSRPKSSQIG-------AVVSHQSSVIPDREYLRK 186

  Fly   179 IGQRLNTWLGKQPEEIPMPHNWGGYILTPSLYEFGMLSGEKAGRT-----RVRFRRCL---EMPR 235
            ..:.|....  |.:|:|.|.:||||:|.|.:.||..      |:|     |:.|||.|   :.|.
Human   187 KNEELEQLY--QDQEVPKPKSWGGYVLYPQVMEFWQ------GQTNRLHDRIVFRRGLPTGDSPL 243

  Fly   236 G--TRVGHVQAERQDWVYD 252
            |  |..|     .:||:|:
Human   244 GPMTHRG-----EEDWLYE 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31473	NP_731188.1	PdxH	40..229	CDD:440029	59/205 (29%)
PNPO	NP_060599.1	pdxH	57..261	CDD:273138	65/222 (29%)