Protein Alignment CG31454 and tmem135

DIOPT Version :9

• Sequence 1: NP_731250.1
• Gene: CG31454 / 318744
• FlyBaseID: FBgn0051454
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: XP_002936590.2
• Gene: tmem135 / 100497844
• XenbaseID: XB-GENE-954105
• Length: 454
• Species: Xenopus tropicalis
• Alignment Length: 493
• Identity: 149/493 - (30%)
• Similarity: 238/493 - (48%)
• Gaps: 82/493 - (16%)

  Fly     1 MAAQSKLAEAAYKCSCQEFVHPWTSSCACATAGMLLSLIPG----TFKTYSMVYMLALLMRRRIP 61
            |||.||    :...||.|..|.|..||    .|..|.:..|    .||.|:.:|::|.::||
 Frog     1 MAALSK----SIPHSCYEIGHTWNPSC----FGSYLQITQGAMEEAFKIYAPLYLVAAILRR--- 54

  Fly    62 SLKDLG----RTLASTLQSTAFLSLNGSLFVLAICLVRQFLGGFYFATAAWLPALLVSSISLAVE 122
              |:|.    :.|...||||:||:.||||::...|::|:.||.|||.|..:..||..|..::.:|
 Frog    55 --KNLDYYIHKLLPELLQSTSFLTANGSLYIAFFCILRKLLGRFYFWTPGFGAALPASYAAILIE 117

  Fly   123 RPQRRAPLALYVANVGIETLWKMLEARGLVRSIAKGQVLIMGASITALMYLY----RAGLHRTVA 183
            |..||..|.:|:||...|.|::|...||.::.|..|:||:.  .|||.:|::    |.||
 Frog   118 RKSRRGLLTIYMANQATEALFRMSVTRGYIKPIRHGEVLLF--CITAALYMFFFRCRDGL----- 175

  Fly   184 KDATFKGLGLIIGREEEGPLKPSTVIIPQ------------------RSNLGSLNFRCITSYLKV 230
            |...|..|..|:|:||    .|:..::|:                  ||::..|
 Frog   176 KGFAFSALKFIVGKEE----IPAHTLVPESMYARAEEKKSKEQRGLSRSSIKKL----------- 225

  Fly   231 YNHLTTL-----RHPCCPH-QFGCAVYALLGGVKPFLGGVGVQVGFKLLLNITRILQQKMEWRKQ 289
               :.|:     ||.||.| :..|..|.:.|.::.|..|..:|...::......:..:.......
 Frog   226 ---MDTICKHGPRHRCCKHYEDNCISYCVKGFIRMFSIGYLIQCCLRIPSTFRHLFTKPSRLLSL 287

  Fly   290 IFNKGSLQLGLALGIFSLLFKMSSCGLRHSFGYDNALFAIQSGLIGSFGLLHFPNTTVSLYLMLK 354
            .:||.:.|||..||.|..::|.:||.||.....|:.|.||.:|.:....::.:.:||:|:||..|
 Frog   288 FYNKENFQLGAFLGSFVSIYKGTSCFLRWVRNLDDELHAIVAGFLAGISMMFYKSTTISMYLASK 352

  Fly   355 SLQLLYNWGVAEEKVPEVPHFSMIMYGFFTAVLCHSTVLEAKSMRPSYFKFIENISGGRLSRFNM 419
            .::.:|..|:...|.|..||...::|...||:..|:.|:|.:::||||:||::.::.||.:..|.
 Frog   353 LVETMYFKGIEAGKCPYFPHADSVIYAVSTAICFHAAVMEVQNLRPSYWKFLQRLTKGRFALMNR 417

  Fly   420 KSFEAFGVKSQDQANYIIKKLG----IVKSSSNPLFPL 453
            |:.:.|..::....|..:.||.    :||    |..||
 Frog   418 KALDVFDSEASKTFNNFVPKLDPRFCVVK----PELPL 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31454	NP_731250.1	TMEM135_C_rich	15..145	CDD:292604	51/137 (37%)
tmem135	XP_002936590.2	TMEM135_C_rich	9..142	CDD:374269	52/141 (37%)
		Tim17	<295..347	CDD:367093	18/51 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	147	1.000	Domainoid score	I4467
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11295
Inparanoid	1	1.050	235	1.000	Inparanoid score	I3309
OMA	1	1.010	-	-		QHG49433
OrthoDB	1	1.010	-	-		D378483at33208
OrthoFinder	1	1.000	-	-		FOG0004145
OrthoInspector	1	1.000	-	-		otm48709
Panther	1	1.100	-	-	O	PTHR12459
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3968
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	11.170