Protein Alignment ric8a and Ric8b

DIOPT Version :10

• Sequence 1: NP_572550.2
• Gene: ric8a / 31874
• FlyBaseID: FBgn0028292
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_001424899.1
• Gene: Ric8b / 314681
• RGDID: 631419
• Length: 560
• Species: Rattus norvegicus
• Alignment Length: 594
• Identity: 195/594 - (32%)
• Similarity: 306/594 - (51%)
• Gaps: 65/594 - (10%)

  Fly     2 ETEHLKRLEAKEADHIPAILDEFNTKNADLLVFDSFRTDNLWHELWLAIFGILDDQRLSHLHTQC 66
            |...|..:.|.||..|..:|.:::.|:.....|:|...|.. .:|...||.:|.....:.....|
  Rat     3 EERALYIVRAGEAGAIERVLRDYSDKHRATFKFESADEDKR-KKLCEGIFKVLVKGVPTTCQVPC 66

  Fly    67 LNTVRILTRDEFSLQTNYIEQEVNTLLKLARIEAGSLKLPATPDELKQEEREEPQLEPSQAQSEV 131
            |..:|||:||:..|.....|:.:..||:||       ||..:.|.|::           .::..|
  Rat    67 LEVLRILSRDKKILAPVTTEENMQILLRLA-------KLHESDDSLEK-----------VSEFPV 113

  Fly   132 IAEALKCLCNLVYQSSDCRRQCLRQHCLDAILKRVASSMRHPCA-------LEYYDMKLLFLLTA 189
            |.|:||||||:|:.|     |..:|..|:..|.....::...|.       ::.:|::|||:|:.
  Rat   114 IVESLKCLCNIVFNS-----QVAQQLSLELNLAAKLCNLLRKCKDRKFINDIKCFDLRLLFVLSL 173

  Fly   190 LEPAARSRLQIDLNGLTYMT---------KWLD------DKLGEDSVGEEQLNIICELLKVMFNV 239
            |....||:|:.:|.||..:|         ||.|      |..| ..:..::.:...|.||.:|||
  Rat   174 LHTDIRSQLRYELQGLPLLTQILESAFSIKWTDEYESAIDHSG-PPLSPQETDCAIEALKALFNV 237

  Fly   240 TSAPDKSPNEYEIQSLH-LTGVLRELLLRFGDLATEKDRAVVTHAINLLTNISGSCLTELTLRCS 303
            |....|...|.:..... :..|||..||..|. ..:|...:.::|:|||:|:..|||..|....:
  Rat   238 TVDSWKVHKESDSHQFRVMAAVLRHCLLIVGP-TEDKTEELHSNAVNLLSNVPVSCLDVLICPLT 301

  Fly   304 NAELESH----KEREQDNEKEKDTEAGAGAKPRECCSQCFEKRNVRSLDVLLRYLRQSLAQQEAE 364
            :.|....    .|...|...||||...:.|       ..:...|:.::.|||.::.:.:   :..
  Rat   302 HEETAQEAATLDELPGDKTAEKDTALKSSA-------MVYNGMNMEAIHVLLSFMEKRI---DKG 356

  Fly   365 ASSHELLSPVLTVLVKCARSDRVMRHYLRQEILPPLRDVSQRPEVGQELRNHLCRFLTLPAMILR 429
            :|..|.|:|||::|.:|:|:.|.:|.:|:.::|||||||:.|||||..:||.|.|.:|...:.::
  Rat   357 SSYREGLTPVLSLLTECSRAHRNIRKFLKDQVLPPLRDVTNRPEVGSTVRNKLVRLMTHVDLGVK 421

  Fly   430 DLSAELLFVLCKENVGRMIKYTGYGNAAGLFAKRGILDCRRVEGTDYSSDSEDSDTEEYKQQQQG 494
            .::||.|||||||.|..::|||||||||||.|.||:|...|  |.::.|:.||:||||||..:..
  Rat   422 QIAAEFLFVLCKERVDSLLKYTGYGNAAGLLAARGLLAGGR--GDNWYSEDEDTDTEEYKNAKPN 484

  Fly   495 INPVLGCVEPRSKSHLDDISEEQKEYEAMQLVNLIEQLRQGGIVKPAMIDKDGRPQPLEHILQLQ 559
            ||.:.|.:|....:.:|:::|||||||||:|||::::|.:..::||..:..||...|||..|...
  Rat   485 INLITGHLEEPMPNPIDEMTEEQKEYEAMKLVNMLDKLSREELLKPMGLKPDGTITPLEEALSQY 549

  Fly   560 EELPQQQLD 568
            ..:.:...|
  Rat   550 SVIEETSSD 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ric8a	NP_572550.2	Ric8	66..534	CDD:462973	171/494 (35%)
Ric8b	NP_001424899.1	None