DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31436 and CG31370

DIOPT Version :9

Sequence 1:	NP_733096.1	Gene:	CG31436 / 318734	FlyBaseID:	FBgn0051436	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_733095.2	Gene:	CG31370 / 43060	FlyBaseID:	FBgn0051370	Length:	396	Species:	Drosophila melanogaster

Alignment Length:	408	Identity:	191/408 - (46%)
Similarity:	268/408 - (65%)	Gaps:	28/408 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 DELVPPEWLNSEFMARVLEGNELEAAVKVIDLTFSPASAKGDHYASIMFRARVKYTNRKGEFQKS 77
            |:|..|||||.:|:..||..:|.|..::|..|.|:|.|||||:|||::.||||:|..:||.|.||
  Fly     8 DQLNVPEWLNEQFVTDVLRSHEKEPDLRVTKLDFTPGSAKGDNYASVIIRARVEYITQKGFFSKS 72

  Fly    78 LIIKTMPEAEGHKKDMLGGSPIFETEMGLYTKVLPEFERILRQVGDDTQLYVNCIYHSLEPHQVL 142
            |||||:.|       |..||.:|:||:|:|.||||||.||||:..|.::||..|||:||||.||:
  Fly    73 LIIKTVLE-------MFAGSALFKTEIGMYRKVLPEFARILRENNDTSRLYAECIYYSLEPSQVM 130

  Fly   143 IFEDLAEMGYIVLRDRDATLDEIRRIYFKLAKWHAVSLKVQNEQPEFLESYTHGLFEMPHVLNDP 207
            |||||.||.|.::|||..|..||...|.||||:||:|:|:.||:|||::.:..|:.    :::.|
  Fly   131 IFEDLGEMDYAMVRDRVLTHGEICGAYSKLAKFHALSMKIINERPEFVKEFKDGIC----LVDIP 191

  Fly   208 FMRTGMEFFVELLGKEPELNKYKPYFESIKDDFLERLVEEWKDIRKSQKKDE---YWVLCHGDLH 269
            :|.:||..|.:.||:.|||::||.:||.|:..|::||    :||.|..:.:.   |:||||||.|
  Fly   192 YMSSGMGPFKDFLGRIPELDRYKTHFEKIEVHFIDRL----RDIMKEYQTNPQPGYYVLCHGDYH 252

  Fly   270 LRNIMFKH-KDTVSLEDCMLLDFQISNLFPLTFDLLYSIYMLLEPEHRWNNWDDLINYYISVLQD 333
            .||||.|| |::...|||||||:|...:.||.|||:||||||:..|.|....:.|:|||.|||::
  Fly   253 TRNIMVKHNKESGGFEDCMLLDYQGCYVAPLAFDLMYSIYMLMNREQRIGELETLLNYYFSVLRE 317

  Fly   334 VLKKIGYKGVMPSQSGLWKRLHQHKYYEFFLISTFLPLMWALRDKSVDFGDLLQNEEKRRKCSFS 398
            .|:||||:|.:|.....||.:::.|.|||..:||:||:...|..::.      .|||...|.
  Fly   318 TLRKIGYQGKLPDPPAFWKEMYRLKDYEFLFLSTYLPMSVGLSLETA------TNEETDDKL--- 373

  Fly   399 KGYIKEVTILLARLDQLG 416
            :.:|:|...:|||.::.|
  Fly   374 QDFIEECKSILARFERSG 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31436	NP_733096.1	EcKinase	52..340	CDD:281023	148/291 (51%)
CG31370	NP_733095.2	EcKinase	47..324	CDD:281023	148/291 (51%)
CG31370	NP_733095.2	APH	<202..320	CDD:279908	59/121 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463765
Domainoid	1	1.000	170	1.000	Domainoid score	I7789
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	1	1.000	-	-		H120121
Inparanoid	1	1.050	224	1.000	Inparanoid score	I5909
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25766
OrthoDB	1	1.010	-	-		D279272at33208
OrthoFinder	1	1.000	-	-		FOG0007618
OrthoInspector	1	1.000	-	-		otm49696
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5704
	12	11.910