DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17754 and AT5G48980

DIOPT Version :9

Sequence 1:	NP_572549.2	Gene:	CG17754 / 31873	FlyBaseID:	FBgn0030114	Length:	654	Species:	Drosophila melanogaster
Sequence 2:	NP_199709.1	Gene:	AT5G48980 / 834957	AraportID:	AT5G48980	Length:	399	Species:	Arabidopsis thaliana

Alignment Length:	420	Identity:	75/420 - (17%)
Similarity:	135/420 - (32%)	Gaps:	143/420 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   225 KLLSSDDLNVPS-EQDVFHSLMSWVRHDSAAREQHIPELLALV----RLPLLQPAF-----IMDH 279
            |.||:|..:.|| ..||...:::.|.......       |:||    |..|..|..     ::..
plant    23 KKLSNDTTSNPSLPYDVILIILARVSRSYYTN-------LSLVSKSFRSILTSPELYKTRTLLGK 80

  Fly   280 VEN---VC-----NANECQQLVMEAFKWHLMPERRSRIATERTTPR---------KSTVGRLLAV 327
            .||   ||     .||.         :|..:..:.::..|:.||.:         ||:|..|..:
plant    81 TENFLYVCLRFPDEANP---------RWFTLYRKPNQTLTDHTTKKKKKKKKKEEKSSVNLLAPI 136

  Fly   328 GGMDAHKGAISIESYCPRLDKWTPWKHMTGRRLQFGAAVMEDKLILVGGRDGLKT-LNTVESLDL 391
            ..:::|.                         :::.|.:..|..:.....|..|. .:.|..||.
plant   137 SILNSHP-------------------------VEWSAIISVDHYLYAISADIEKAPYSNVPYLDC 176

  Fly   392 NTMAW--APLNAMATPRHGLGVAVLEGPLYAVGGHDGWSYLNTVERWDPIARTWSYVAPMSSMRS 454
            .|..|  ||...:|...     :..||.:|..|..:....||.||.::.:.:||..|.|..
plant   177 RTHTWNEAPRMRLAHTN-----SEFEGIVYLPGSFESPDSLNCVEVYNTMTQTWKPVPPEK---- 232

  Fly   455 TAGVAVLGGRLYAVGGRDGSVCHRSIECYDPHTNKWSLLAPMNRRRGGVGVTVANGFLYALGGHD 519
                     |::.:...:..:.::|.     |.:.          |.|.|::::.
plant   233 ---------RMFKLENLEKKIYYKSF-----HLDS----------RAGKGLSLSY---------- 263

  Fly   520 CPASNPMVCRTETVERYDPATDTWTLICSLAL----------GRDAIGCALLGDRLIVVGGYDGN 574
              .|..:.|....::..|....:..:|.::|.          |.|.        :::|.|..:|.
plant   264 --KSKHLTCGLVVLDTVDSYLRSSCMIENIAYFYRKGNFIWRGLDG--------KILVYGKIEGL 318

  Fly   575 HALKSVEEYDPVRNG---------WNELAP 595
            ..|.....|..|:..         |::..|
plant   319 EGLPKFSRYSSVQLAEYGGKLVVLWDKYVP 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17754	NP_572549.2	BTB	70..170	CDD:279045
		PHA03098	71..591	CDD:222983	73/414 (18%)
		BACK	179..281	CDD:285009	15/65 (23%)
		Kelch	323..369	CDD:128874	3/45 (7%)
		KELCH repeat	359..402	CDD:276965	11/45 (24%)
		Kelch	370..416	CDD:128874	10/48 (21%)
		KELCH repeat	406..449	CDD:276965	11/42 (26%)
		Kelch	418..463	CDD:128874	10/44 (23%)
		KELCH repeat	453..497	CDD:276965	3/43 (7%)
		Kelch	464..510	CDD:128874	6/45 (13%)
		Kelch_1	499..546	CDD:279660	6/46 (13%)
		KELCH repeat	500..549	CDD:276965	7/48 (15%)
		KELCH repeat	553..596	CDD:276965	9/52 (17%)
		Kelch	564..610	CDD:128874	8/41 (20%)
AT5G48980	NP_199709.1	F-box	34..75	CDD:279040	10/47 (21%)
		KELCH repeat	148..187	CDD:276965	11/38 (29%)
		Kelch_1	187..230	CDD:279660	12/47 (26%)
		KELCH repeat	188..230	CDD:276965	12/46 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X9
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910