| Sequence 1: | NP_572549.2 | Gene: | CG17754 / 31873 | FlyBaseID: | FBgn0030114 | Length: | 654 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_476503.1 | Gene: | KLHL4 / 56062 | HGNCID: | 6355 | Length: | 720 | Species: | Homo sapiens |
| Alignment Length: | 580 | Identity: | 315/580 - (54%) |
|---|---|---|---|
| Similarity: | 405/580 - (69%) | Gaps: | 16/580 - (2%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 22 ISMLADNTLESLSRDYSLGSLNSAGSQD-------EFFRCRDHADNILKRMQLYVDSQQLCDVVL 79
Fly 80 IAGIDGKRVPAHRLVLSASSAYFSAMFTGSLRETKEQEVTLGEVHGDALHLLVQYCYTGFIEMRE 144
Fly 145 DTVETLLATACLLQLNAVVTACCNFLARQLHPSNCLGFAFFAEQQSCTTLLRLAQAYTCQYFMQV 209
Fly 210 CQNQEFFQLNADQLGKLLSSDDLNVPSEQDVFHSLMSWVRHDSAAREQHIPELLALVRLPLLQPA 274
Fly 275 FIMD-HVENVCNAN-ECQQLVMEAFKWHLMPERRSRIATERTTPRKSTVGRLLAVGGMDAHKGAI 337
Fly 338 SIESYCPRLDKWTPWKHMTGRRLQFGAAVMEDKLILVGGRDGLKTLNTVESLDLNTMAWAPLNAM 402
Fly 403 ATPRHGLGVAVLEGPLYAVGGHDGWSYLNTVERWDPIARTWSYVAPMSSMRSTAGVAVLGGRLYA 467
Fly 468 VGGRDGSVCHRSIECYDPHTNKWSLLAPMNRRRGGVGVTVANGFLYALGGHDCPASNPMVCRTET 532
Fly 533 VERYDPATDTWTLICSLALGRDAIGCALLGDRLIVVGGYDGNHALKSVEEYDPVRNGWNE 592 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG17754 | NP_572549.2 | BTB | 70..170 | CDD:279045 | 56/99 (57%) |
| PHA03098 | 71..591 | CDD:222983 | 298/521 (57%) | ||
| BACK | 179..281 | CDD:285009 | 48/102 (47%) | ||
| Kelch | 323..369 | CDD:128874 | 25/45 (56%) | ||
| KELCH repeat | 359..402 | CDD:276965 | 24/42 (57%) | ||
| Kelch | 370..416 | CDD:128874 | 27/45 (60%) | ||
| KELCH repeat | 406..449 | CDD:276965 | 36/42 (86%) | ||
| Kelch | 418..463 | CDD:128874 | 33/44 (75%) | ||
| KELCH repeat | 453..497 | CDD:276965 | 29/43 (67%) | ||
| Kelch | 464..510 | CDD:128874 | 31/45 (69%) | ||
| Kelch_1 | 499..546 | CDD:279660 | 28/46 (61%) | ||
| KELCH repeat | 500..549 | CDD:276965 | 27/48 (56%) | ||
| KELCH repeat | 553..596 | CDD:276965 | 23/40 (58%) | ||
| Kelch | 564..610 | CDD:128874 | 17/29 (59%) | ||
| KLHL4 | NP_476503.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 46..69 | ||
| BTB | 172..276 | CDD:279045 | 59/105 (56%) | ||
| PHA03098 | 176..698 | CDD:222983 | 298/523 (57%) | ||
| BACK | 284..373 | CDD:285009 | 41/88 (47%) | ||
| Kelch 1 | 430..476 | 25/45 (56%) | |||
| Kelch | 431..476 | CDD:128874 | 25/44 (57%) | ||
| Kelch_1 | 465..510 | CDD:279660 | 25/44 (57%) | ||
| KELCH repeat | 466..509 | CDD:276965 | 24/42 (57%) | ||
| Kelch 2 | 477..523 | 27/45 (60%) | |||
| KELCH repeat | 513..557 | CDD:276965 | 36/43 (84%) | ||
| Kelch 3 | 525..570 | 33/44 (75%) | |||
| Kelch | 526..570 | CDD:128874 | 33/43 (77%) | ||
| KELCH repeat | 560..603 | CDD:276965 | 28/42 (67%) | ||
| Kelch | 571..617 | CDD:128874 | 31/45 (69%) | ||
| Kelch 4 | 571..617 | 31/45 (69%) | |||
| KELCH repeat | 607..658 | CDD:276965 | 28/50 (56%) | ||
| Kelch | 619..670 | CDD:128874 | 23/50 (46%) | ||
| Kelch 5 | 619..670 | 23/50 (46%) | |||
| Kelch_1 | 659..702 | CDD:279660 | 23/41 (56%) | ||
| KELCH repeat | 660..699 | CDD:276965 | 22/38 (58%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 119 | 1.000 | Domainoid score | I5797 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG4441 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 691 | 1.000 | Inparanoid score | I690 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG48972 | |
| OrthoDB | 1 | 1.010 | - | - | D312716at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000036 | |
| OrthoInspector | 1 | 1.000 | - | - | otm42190 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_104433 | |
| Panther | 1 | 1.100 | - | - | O | PTHR24412 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X9 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 13 | 12.840 | |||||