Protein Alignment CG17754 and ivns1abpa

DIOPT Version :10

• Sequence 1: NP_572549.2
• Gene: CG17754 / 31873
• FlyBaseID: FBgn0030114
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: NP_954973.2
• Gene: ivns1abpa / 387591
• ZFINID: ZDB-GENE-031222-2
• Length: 643
• Species: Danio rerio
• Alignment Length: 632
• Identity: 171/632 - (27%)
• Similarity: 286/632 - (45%)
• Gaps: 100/632 - (15%)

  Fly    48 QDEFFRCRDHADNILKRMQLYVDSQQLCDVVLIAGIDGKRVPAHRLVLSASSAYFSAMFTGSLRE 112
            :||.|     .|:.:.:|.....:.|.|||.|  .:.|..:.|||.||:..|.|...:|...|..
Zfish    10 EDESF-----LDSTVAKMNALRKNGQFCDVRL--QVCGHELMAHRAVLACCSPYLFEIFNSDLEP 67

  Fly   113 TKEQEVTLGEVHGDALHLLVQYCYTGFIEMREDTVETLLATACLLQLNAVVTACCNFLARQLHPS 177
            .....|...::..:|:.:|:.|.||..::..::.|:.:.:.|..|:::.|...|.::|..::...
Zfish    68 HGISHVKFEDLDPEAVEILLNYAYTAQLKADKELVKEVYSAAKRLKMDRVKQICGDYLLSKMDSQ 132

  Fly   178 NCLGFAFFAEQQSCTTLLRLAQAYTCQYFMQVCQNQEFFQLNADQLGKLLSSDDLNVPSEQDVFH 242
            :.:.:..||.......||....:|..::.::|.:.::|.:|...:| :::..|:|.:||...::.
Zfish   133 SAISYRNFASCMGDGRLLGKIDSYIQEHLLEVSEQEDFLKLPRLKL-EVMLEDNLTLPSNGKLYS 196

  Fly   243 SLMSWVRHDSAAREQHIPELLALVRL-------PLLQPAFI----------MDHV---------E 281
            .::.||:.......:.:..|:..|:.       .||..:.:          .||:         |
Zfish   197 KVIGWVQRSLWENGEPLERLMEEVQTLYYSADHKLLDGSLLDGQAEVFGTEDDHIQFVQKKPPRE 261

  Fly   282 NV---------------CNANECQQLVMEAFKWHLMPERRSRIATERTTPRK----STVGRLLAV 327
            ||               ...:.|:|      :|       ..||:|:||...    :.:..:|.|
Zfish   262 NVHRQLSTSSSGSLSPGSTKHPCKQ------EW-------KYIASEKTTNNTYLCLAVLNGMLCV 313

  Fly   328 GGMDAHKGAISIESYCPRLDKWTPWKHMTGRRLQ----------------FGAAVMEDKLILVGG 376
            ..:.......:..|..|.|.|...::   |:.|:                .|.|.:.|:||..||
Zfish   314 IFLHGRSSPQASPSATPCLTKSLSFE---GQPLEEEPDKLLSPMHYARSGLGIASLNDQLIAAGG 375

  Fly   377 RDGLKTLNTVESLDLNTMAWAPLNAMATPRHGLGVAVLEGPLYAVGGHDGWS-YLNTVERWDPIA 440
            .:..:.|.|||..::.|.:|..:..|.|||....:|||.|.||.:||.:|.| .|:..|.::|.|
Zfish   376 YNREECLRTVECYNIKTNSWTFIAPMRTPRARFQMAVLMGQLYVMGGSNGHSDELSCGETYNPNA 440

  Fly   441 RTWSYVAPMSSMRSTAGVAVLGGRLYAVGGRD--GSVCHRSIECYDPHTNKWSLLAPMNRRRGGV 503
            ..|:.|..:.:.|..|||..|..:||.|||.|  |....::.:.:||.:..|:..||:|.||...
Zfish   441 DEWTQVPELRTNRCNAGVCSLNNKLYVVGGSDPCGQKGLKNCDVFDPISKAWTNCAPLNIRRHQA 505

  Fly   504 GVTVANGFLYALGGHD---CPASNPMVCRTETVERYDPATDTWTLICSLALGRDAIGCALLGDRL 565
            .|...:||:|.:||.:   |         ..:||||:|..:|||||.|:.:.|...|.|:...:|
Zfish   506 AVCELDGFMYVIGGAESWNC---------LNSVERYNPENNTWTLIASMNIARRGAGVAVYEGKL 561

  Fly   566 IVVGGYDGNHALKSVEEYDPVRNGWNELAPMAFARAGACVVAIPNVI 612
            .||||:||:|||:.||.||||||.|..|..|...|:.|....:.:||
Zfish   562 FVVGGFDGSHALRCVEMYDPVRNEWRMLGSMNSPRSNAGAAVLNDVI 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17754	NP_572549.2	PHA03098	71..591	CDD:222983	159/586 (27%)
		KELCH repeat	359..402	CDD:276965	14/58 (24%)
		KELCH repeat	406..449	CDD:276965	17/43 (40%)
		KELCH repeat	453..497	CDD:276965	17/45 (38%)
		KELCH repeat	500..549	CDD:276965	18/51 (35%)
		KELCH repeat	553..596	CDD:276965	23/42 (55%)
ivns1abpa	NP_954973.2	BTB_POZ_NS1BP	14..137	CDD:349615	30/129 (23%)
		BACK_NS1BP_IVNS1ABP	129..225	CDD:350577	17/96 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	257..282		3/24 (13%)
		NanM	351..613	CDD:442289	99/267 (37%)
		KELCH repeat	358..401	CDD:276965	13/42 (31%)
		Kelch 1	369..415		17/45 (38%)
		KELCH repeat	405..450	CDD:276965	17/44 (39%)
		Kelch 2	416..463		17/46 (37%)
		KELCH repeat	453..498	CDD:276965	16/44 (36%)
		Kelch 3	465..512		16/46 (35%)
		KELCH repeat	502..545	CDD:276965	18/51 (35%)
		Kelch 4	513..559		19/54 (35%)
		KELCH repeat	549..593	CDD:276965	23/43 (53%)
		Kelch 5	560..606		23/45 (51%)
		Kelch_1	595..638	CDD:396078	4/14 (29%)
		KELCH repeat	596..638	CDD:276965	4/13 (31%)
		Kelch 6	608..643		1/1 (100%)