Protein Alignment CG17754 and enc3

DIOPT Version :10

• Sequence 1: NP_572549.2
• Gene: CG17754 / 31873
• FlyBaseID: FBgn0030114
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: NP_001001402.2
• Gene: enc3 / 327531
• ZFINID: ZDB-GENE-030131-5742
• Length: 589
• Species: Danio rerio
• Alignment Length: 613
• Identity: 174/613 - (28%)
• Similarity: 286/613 - (46%)
• Gaps: 57/613 - (9%)

  Fly    32 SLSRDYSLGSLNSAGSQD-EFFRCRDHADNILKRMQLYVDSQQLCDVVLIAGIDGKRV-PAHRLV 94
            |:|...:..|.:|:||.: :.|....|||::|..:.|....:...||||.|   |.|| |.||.|
Zfish     2 SVSNHENRKSRSSSGSMNIQLFHKTSHADSLLTHLNLLRKRRVFTDVVLRA---GHRVFPCHRAV 63

  Fly    95 LSASSAYFSAMFTGSLRETKEQEVTLGE-VHGDALHLLVQYCYTGFIEMREDTVETLLATACLLQ 158
            |::.|.||.|||:|.|:|:::.||...: :|.:.|.||:.|.|:..:.:.|:..|:||....:||
Zfish    64 LASCSRYFEAMFSGGLKESRDAEVNFHDSLHPEVLELLLDYAYSARVIINEENAESLLEAGDMLQ 128

  Fly   159 LNAVVTACCNFLARQLHPSNCLGFAFFAEQQSCTTLLRLAQAYTCQYFMQVCQNQEFFQLNADQL 223
            .:.:..|...||.:.||||||||....::...|..|..|:.......|..:...::|..|..|::
Zfish   129 FHDIRDAASEFLEKNLHPSNCLGMMLLSDAHQCQRLYELSWRMCLANFANLYHTEDFLSLPKDKV 193

  Fly   224 GKLLSSDDLNVPSEQDVFHSLMSWVRHDSAAREQHIPELLALVRLPLLQPAFIMDHV---ENVCN 285
            .:|:.|::|.|..|..|:.:::.|||.|...|...:|:||..|||.||...:::.:|   |.|..
Zfish   194 QELVFSEELEVEDESIVYEAVIDWVRADIGRRHLDLPDLLRCVRLALLPETYLLKNVASEELVMG 258

  Fly   286 ANECQQLVMEAFKWHLMPERRSRIATE-RTTPRKSTVGRLLAVGG---------MDAHKGAISIE 340
            ....:::|.:|.:..:...:...:.|. ...|||.:.. ||.:||         |..||.    :
Zfish   259 HKVGREIVEDAVRCKMKILQNDGVVTGFCARPRKVSQA-LLLLGGQTFMCDKVYMIDHKA----K 318

  Fly   341 SYCPRLDKWTPWKHMTGRRLQFGAAVMEDKLILVGGRDGLKTLNTVESLDLNTM--AWAPLNAMA 403
            ...|:.|..:|       |.:..|..:..|:.:.||| |.:...:.:....:|:  .|:....|.
Zfish   319 EITPKTDLPSP-------RKECSACAIGCKVYVTGGR-GSENGASKDVWVYDTLHDEWSKAAQML 375

  Fly   404 TPRHGLGVAVLEGPLYAVGGHDGWS---------YLNTVERWDPIARTWSYVAPMSSMRSTAGVA 459
            ..|.|.|.|.|:..||.||||...:         .|..||:::|.:..|:.|||:....|.|.|.
Zfish   376 VARFGHGSAELDHILYVVGGHTSLAGSFPASPSVSLKQVEQYNPQSNKWTLVAPLREGVSNAAVV 440

  Fly   460 VLGGRLYAVGG----RDGSVCHRSIECYDPHTNKWSLLAPMNRRRGGVGVTVANGFLYALGGHDC 520
            ....:|:|.||    ||.   :..::|:||..|:|::.|...:........|....:..:|| |.
Zfish   441 GAKNKLFAFGGTSVNRDK---YPKVQCFDPCENRWTVPATCPQLWRYTAAAVVGNHVVVIGG-DT 501

  Fly   521 PASNPMVCRTETVERYDPATDTWTLICSLALGRDAIGCALLGDRLIVVGGYDGNHALKSVEEYDP 585
            ..|      ..:..|::..|..||....:...|.:......|:||.|||||.|....|:::.|||
Zfish   502 EFS------ASSAYRFNSETFQWTKFGDVTSKRISCHAVASGNRLYVVGGYFGAQRCKTLDCYDP 560

  Fly   586 VRNGWNELAPMAFARAGACVVAIPNVIP 613
            ..:.|:.:..:.::......|:....:|
Zfish   561 STDSWDSITSVPYSLIPTAFVSTWKYLP 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17754	NP_572549.2	PHA03098	71..591	CDD:222983	159/549 (29%)
		KELCH repeat	359..402	CDD:276965	9/44 (20%)
		KELCH repeat	406..449	CDD:276965	18/51 (35%)
		KELCH repeat	453..497	CDD:276965	15/47 (32%)
		KELCH repeat	500..549	CDD:276965	9/48 (19%)
		KELCH repeat	553..596	CDD:276965	15/42 (36%)
enc3	NP_001001402.2	BTB_POZ	6..152	CDD:453885	56/148 (38%)
		PHA03098	60..566	CDD:222983	150/528 (28%)
		BACK_KLHL25_like	145..242	CDD:350539	32/96 (33%)
		KELCH repeat	330..374	CDD:276965	9/44 (20%)
		KELCH repeat	378..431	CDD:276965	19/52 (37%)
		KELCH repeat	434..480	CDD:276965	15/48 (31%)
		KELCH repeat	528..570	CDD:276965	15/41 (37%)