Protein Alignment CG17754 and Enc1

DIOPT Version :10

• Sequence 1: NP_572549.2
• Gene: CG17754 / 31873
• FlyBaseID: FBgn0030114
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: NP_001003401.1
• Gene: Enc1 / 294674
• RGDID: 1303152
• Length: 589
• Species: Rattus norvegicus
• Alignment Length: 592
• Identity: 175/592 - (29%)
• Similarity: 276/592 - (46%)
• Gaps: 56/592 - (9%)

  Fly    38 SLGSLNSAGSQDEFFRCRDHADNILKRMQLYVDSQQLCDVVLIAGIDGKRVPAHRLVLSASSAYF 102
            |.||:|.     ..|....:||::|..:.|....:...||:|.||  .:..|.||.||:|.|.||
  Rat    14 SSGSINI-----YLFHKSSYADSVLTHLNLLRQQRLFTDVLLHAG--NRTFPCHRAVLAACSRYF 71

  Fly   103 SAMFTGSLRETKEQEVTL-GEVHGDALHLLVQYCYTGFIEMREDTVETLLATACLLQLNAVVTAC 166
            .|||:|.|:|:::.||.. ..:|.:.|.||:.|.|:..:.:.|:..|:||....:|:...:..||
  Rat    72 EAMFSGGLKESQDSEVNFDNSIHPEVLELLLDYAYSSRVIINEENAESLLEAGDMLEFQDIRDAC 136

  Fly   167 CNFLARQLHPSNCLGFAFFAEQQSCTTLLRLAQAYTCQYFMQVCQNQEFFQLNADQLGKLLSSDD 231
            ..||.:.|||:||||....::...||.|..|:.......|..:.:|::|.||..|.:.:||||::
  Rat   137 AEFLEKNLHPTNCLGMLLLSDAHQCTKLYELSWRMCLSNFQTIRKNEDFLQLPQDMVVQLLSSEE 201

  Fly   232 LNVPSEQDVFHSLMSWVRHDSAAREQHIPELLALVRLPLLQPAFIMDHV---ENVCNANECQQLV 293
            |....|:.|:.|.|:|:.:|...|..::||||..|||.||...::|::|   |.:....:.:::|
  Rat   202 LETEDERLVYESAMNWISYDLKKRYCYLPELLQTVRLALLPAIYLMENVAMEELITKQRKSKEIV 266

  Fly   294 MEAFKWHLMPERRSRIATERTTPRKSTVGRLLAVGGMDAHKGAISI-----ESYCPRLDKWTPWK 353
            .||.:..|...:...:.|......:.|...|..:||.......:.:     :...|:.|..:|
  Rat   267 EEAIRCKLKILQNDGVVTSLCARPRKTGHALFLLGGQTFMCDKLYLVDQKAKEIIPKADIPSP-- 329

  Fly   354 HMTGRRLQFGAAVMEDKLILVGGR---DGLKTLNTVESLDLNTMAWAPLNAMATPRHGLGVAVLE 415
                 |.:|.|..:..|:.:.|||   :|:.  ..|...|.....|:....|...|.|.|.|.|:
  Rat   330 -----RKEFSACAIGCKVYITGGRGSENGVS--KDVWVYDTLHEEWSKAAPMLVARFGHGSAELK 387

  Fly   416 GPLYAVGGHDGWS---------YLNTVERWDPIARTWSYVAPMSSMRSTAGVAVLGGRLYAVGGR 471
            ..||.||||...:         .|..||::||....|:.|||:....|.|.|.....:|:|.||.
  Rat   388 HCLYVVGGHTAATGCLPASPSVSLKQVEQYDPTTNKWTMVAPLREGVSNAAVVSAKLKLFAFGGT 452

  Fly   472 DGSVCH---RSIECYDPHTNKWSLLAPMNRRRGGVGVTVANGFLYALGGHDCPASNPMVCRTETV 533
              ||.|   ..::|||...|:|::.|...:........|....::.:|| |...|   .|   :.
  Rat   453 --SVSHDKLPKVQCYDQCENRWTVPATCPQPWRYTAAAVLGNQIFIMGG-DTEFS---AC---SA 508

  Fly   534 ERYDPATDTWTLICSLALGRDAIGCALLGDRLIVVGGYDGNHALKSVEEYDPVRNGWN------- 591
            .:::..|..||.:..:...|.:......|::|.|||||.|....|:::.|||..:.||
  Rat   509 YKFNSETYQWTKVGDVTAKRMSCHAVASGNKLYVVGGYFGIQRCKTLDCYDPTLDVWNSITTVPY 573

  Fly   592 ELAPMAF 598
            .|.|.||
  Rat   574 SLIPTAF 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17754	NP_572549.2	PHA03098	71..591	CDD:222983	160/543 (29%)
		KELCH repeat	359..402	CDD:276965	11/45 (24%)
		KELCH repeat	406..449	CDD:276965	19/51 (37%)
		KELCH repeat	453..497	CDD:276965	16/46 (35%)
		KELCH repeat	500..549	CDD:276965	9/48 (19%)
		KELCH repeat	553..596	CDD:276965	16/49 (33%)
Enc1	NP_001003401.1	BTB_POZ_KLHL37_ENC1	6..152	CDD:349576	52/144 (36%)
		PHA03098	48..566	CDD:222983	159/537 (30%)
		BACK_KLHL37_ENC1	145..242	CDD:350590	36/96 (38%)
		KELCH repeat	330..374	CDD:276965	11/45 (24%)
		KELCH repeat	378..431	CDD:276965	20/52 (38%)
		KELCH repeat	434..480	CDD:276965	16/47 (34%)
		KELCH repeat	528..568	CDD:276965	15/39 (38%)