DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17754 and C53A5.11

DIOPT Version :9

Sequence 1:	NP_572549.2	Gene:	CG17754 / 31873	FlyBaseID:	FBgn0030114	Length:	654	Species:	Drosophila melanogaster
Sequence 2:	NP_506607.2	Gene:	C53A5.11 / 183741	WormBaseID:	WBGene00008269	Length:	382	Species:	Caenorhabditis elegans

Alignment Length:	333	Identity:	75/333 - (22%)
Similarity:	125/333 - (37%)	Gaps:	75/333 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   331 DAHKGAISIESYCPR-LDKWTPWKHMTGRRLQ-----FGAAVMEDKLILVGGRDGLK-------- 381
            |.|..:.|.|:..|: ::....:::.|...:|     ||....|    |..|:|.||
Worm    21 DYHSDSQSEETQHPKAIEMRNQFRNTTENLIQTLQMFFGILSFE----LYEGKDNLKCITMIHDI 81

  Fly   382 ----------------TLNTVESLDL-------------------------------NTMAWAPL 399
                            |||:.|.:.:                               :||::.|:
Worm    82 TSLMEVADTKLKNYINTLNSKEQIFMVDDGVLNMDPILVADRKQNSREPLFIGYFKPDTMSFMPI 146

  Fly   400 NAMATPRHGLGVAVLEGPLYAVGGHDGWSYLNTVERWDPIARTWSYVAPMSSMRSTAGVAVLGGR 464
            ..:..|:....|......::.:||.:..:|||.||.:|...........:...|:.....:....
Worm   147 GRLPNPKSHYAVVSSSTKVFIIGGMNNGTYLNRVEMFDKEKGIRVECTRLMHGRTRTSACIHEDA 211

  Fly   465 LYAVGGRDGSVCHRSIECYDPHT-NKWSLLAPMNRRRGGVGVTVANGFLYALGGHDCPASNPMVC 528
            :|||||.|.:.. .|:|.||..| ..|:....:|.||....|....|.|:.|||.:.....
Worm   212 IYAVGGYDATYM-SSVEIYDIKTGGDWTTGPSLNNRRADASVVSFYGQLFVLGGFNGKDYE---- 271

  Fly   529 RTETVERYDPATDTWTLICSLALGRDAIGCALLGDRLIVVGGYDGN-HALKSVEEYDPVRNGWNE 592
              ||:|:...:.|.:. :|...:||...|..:...|:.|.||::.. :.||:.:.|||:.|.|.:
Worm   272 --ETIEKLSDSKDKFE-VCGNMVGRAGFGACVFRGRIYVAGGWNTPCNTLKTFQSYDPLTNTWKD 333

  Fly   593 LAPMAFAR 600
            ...|...|
Worm   334 EPSMNTGR 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17754	NP_572549.2	BTB	70..170	CDD:279045
		PHA03098	71..591	CDD:222983	72/322 (22%)
		BACK	179..281	CDD:285009
		Kelch	323..369	CDD:128874	9/43 (21%)
		KELCH repeat	359..402	CDD:276965	16/102 (16%)
		Kelch	370..416	CDD:128874	14/100 (14%)
		KELCH repeat	406..449	CDD:276965	9/42 (21%)
		Kelch	418..463	CDD:128874	9/44 (20%)
		KELCH repeat	453..497	CDD:276965	13/44 (30%)
		Kelch	464..510	CDD:128874	16/46 (35%)
		Kelch_1	499..546	CDD:279660	12/46 (26%)
		KELCH repeat	500..549	CDD:276965	12/48 (25%)
		KELCH repeat	553..596	CDD:276965	13/43 (30%)
		Kelch	564..610	CDD:128874	13/38 (34%)
C53A5.11	NP_506607.2	KELCH repeat	153..197	CDD:276965	9/43 (21%)
		BTB	<165..379	CDD:333434	51/185 (28%)
		KELCH repeat	200..243	CDD:276965	13/43 (30%)
		KELCH repeat	247..290	CDD:276965	12/49 (24%)
		KELCH repeat	293..339	CDD:276965	14/45 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4441
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X9
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.900