Protein Alignment CG17754 and klhl10a

DIOPT Version :10

• Sequence 1: NP_572549.2
• Gene: CG17754 / 31873
• FlyBaseID: FBgn0030114
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: XP_017207208.2
• Gene: klhl10a / 100333629
• ZFINID: ZDB-GENE-131015-1
• Length: 580
• Species: Danio rerio
• Alignment Length: 543
• Identity: 184/543 - (33%)
• Similarity: 277/543 - (51%)
• Gaps: 33/543 - (6%)

  Fly    83 IDGKRVPAHRLVLSASSAYFSAMFTGSLRETK-EQEVTLGEVHGDALHLLVQYCYTGFIEMREDT 146
            :.||....|:::|...|.||..:|  |.:.|| :|.....|:..|.:.|::|:.|...:::.||.
Zfish    25 VHGKVFRVHKIILCGCSPYFRMLF--STQWTKPKQHFNFPEMSSDTMSLIIQHAYARPVQITEDN 87

  Fly   147 VETLLATACLLQLNAVVTACCNFLARQLHPSNCLGFAFFAEQ-QSCTTLLRLAQAYTCQYFMQVC 210
            |..||..|..|.::.:..|||.||.......||:|...|.|: .|||.|...|:.|..|:|.:|.
Zfish    88 VCELLVAADQLLISGLTEACCKFLEANFSLQNCIGIWAFTERFHSCTELHHKAEFYVLQHFQEVQ 152

  Fly   211 Q-NQEFFQLNADQLGKLLSSDDLNVPSEQDVFHSLMSWVRHDSAAREQHIPELLALVRLPLLQPA 274
            | ::||.||..:.|..::|.|:|||..|:.||.:::.|:.|:...|..||..||:.|||.|:.|.
Zfish   153 QVSEEFLQLPLELLENMISRDELNVKQEEVVFEAILRWINHEPENRRNHITALLSRVRLGLMSPE 217

  Fly   275 FIMDHVEN---VCNANECQQLVMEA----FKWHLMPERRSRIA--TERTTPRKSTVGRLLAVGGM 330
            :.|::|.|   |.....|..:::.|    |..|:.|.....::  |.:..|.:.    |||:||.
Zfish   218 YFMNNVRNNPLVLENEACSFIIINAMKVIFDLHVEPTSSGLVSYMTRQRMPSEV----LLAIGGW 278

  Fly   331 DAHKGAISIESYCPRLDKWTPWKHMTGR----RLQFGAAVMEDKLILVGGRDGLKTLNTVESLDL 391
            ........||:|..|.:   .||.:|..    |...|.||::..:..|||.|.....::|...:.
Zfish   279 SIGNPTNGIEAYDTRAN---CWKDVTVENELPRAYHGVAVLDGFIYAVGGFDSENYFSSVRKFNP 340

  Fly   392 NTMAWAPLNAMATPRHGLGVAVLEGPLYAVGGHDGWSYLNTVERWDPIARTWSYVAPMSSMRSTA 456
            .|..|..:..|...|..:.||||:|.|||:||.:|.:.|.|.|.::.....|:.::|||..||.|
Zfish   341 VTHTWHEVAPMYERRCYVSVAVLDGLLYAIGGFNGHARLKTAECYNKNTNQWTQISPMSERRSDA 405

  Fly   457 GVAVLGGRLYAVGGRDGSVCHRSIECYDPHTNKWSLLAPMNRRRGGVGVTVANGFLYALGGHDCP 521
            ....|.|::|..||..|..|..:.|.::|.||:|||:.||..||.||||......:||:||.|..
Zfish   406 SATSLHGKVYICGGFTGVECLFTAESFNPETNQWSLIEPMRTRRSGVGVITFGNLIYAVGGFDGS 470

  Fly   522 ASNPMVCRTETVERYDPATDTWTLICSLALGRDAIGCALLGDRLIVVGGYDGNHALKSVEEYDPV 586
            :      |..:||.|||.||:|..|.|:...|...|..::.|:||||||::|......||.|:..
Zfish   471 S------RLRSVEAYDPHTDSWHDIESMINTRSNFGIEVVNDQLIVVGGFNGFRTCSDVEIYNQS 529

  Fly   587 RNGWNELAPMAFARA--GACVVA 607
            .|.|.|:..|..:|:  ..||::
Zfish   530 TNEWVEVCDMNISRSALSCCVIS 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17754	NP_572549.2	PHA03098	71..591	CDD:222983	178/523 (34%)
		KELCH repeat	359..402	CDD:276965	11/42 (26%)
		KELCH repeat	406..449	CDD:276965	16/42 (38%)
		KELCH repeat	453..497	CDD:276965	18/43 (42%)
		KELCH repeat	500..549	CDD:276965	20/48 (42%)
		KELCH repeat	553..596	CDD:276965	16/42 (38%)
klhl10a	XP_017207208.2	PHA03098	23..551	CDD:222983	183/540 (34%)
		KELCH repeat	308..351	CDD:276965	11/42 (26%)
		KELCH repeat	355..398	CDD:276965	16/42 (38%)
		KELCH repeat	402..446	CDD:276965	18/43 (42%)
		KELCH repeat	449..492	CDD:276965	20/48 (42%)
		KELCH repeat	496..540	CDD:276965	16/43 (37%)