Protein Alignment CG17754 and enc1

DIOPT Version :10

• Sequence 1: NP_572549.2
• Gene: CG17754 / 31873
• FlyBaseID: FBgn0030114
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: XP_002934870.1
• Gene: enc1 / 100271761
• XenbaseID: XB-GENE-966092
• Length: 589
• Species: Xenopus tropicalis
• Alignment Length: 599
• Identity: 178/599 - (29%)
• Similarity: 279/599 - (46%)
• Gaps: 52/599 - (8%)

  Fly    32 SLSRDYSLGSLNSAGSQDEF-FRCRDHADNILKRMQLYVDSQQLCDVVLIAGIDGKRVPAHRLVL 95
            |:|...:..|..|.||.:.: |....:||::|..:.|........||:|:||  .:..|.||.||
 Frog     2 SVSLHENRKSRASTGSMNIYLFHKSSYADSVLTHLNLLRKQCLFTDVLLLAG--NRSFPCHRAVL 64

  Fly    96 SASSAYFSAMFTGSLRETKEQEVTL-GEVHGDALHLLVQYCYTGFIEMREDTVETLLATACLLQL 159
            :|.|.||.|||:|.|:|::..||.. ..||.:.|.||:.|.|:..:.:.|:..|:||....:|:.
 Frog    65 AACSRYFEAMFSGGLKESQANEVNFHSAVHPEVLELLLDYAYSSRVIINEENAESLLEAGDMLEF 129

  Fly   160 NAVVTACCNFLARQLHPSNCLGFAFFAEQQSCTTLLRLAQAYTCQYFMQVCQNQEFFQLNADQLG 224
            ..:..||..||.:.|||:||||....::...||.|..|:.......|..:|:.::|..|..|.:.
 Frog   130 QDIRDACAEFLEKNLHPTNCLGMLLLSDAHQCTKLYELSWRMCLNNFQTICKTEDFLLLPKDLVV 194

  Fly   225 KLLSSDDLNVPSEQDVFHSLMSWVRHDSAAREQHIPELLALVRLPLLQPAFIMDHV---ENVCNA 286
            :|||:::|....|:.|:.|.|:|:.:|...|..::.|||..|||.||...::|::|   |.:...
 Frog   195 QLLSNEELETEDERMVYESAMNWIHYDLNKRHCYLSELLQTVRLALLPAIYLMENVAMEELIIKQ 259

  Fly   287 NECQQLVMEAFKWHLMPERRSRIATERTTPRKSTVGRLLAVGGMDAHKGAISI-----ESYCPRL 346
            .:.::||.||.:..|...:...:.|......:.|...|..:||.......:.:     :...|:.
 Frog   260 KKSKELVEEAIRCKLKILQNDGVVTSLCAKPRKTGHALFLLGGQTFMCDKLYLVDQKAKEIIPKA 324

  Fly   347 DKWTPWKHMTGRRLQFGAAVMEDKLILVGGR---DGLKTLNTVESLDLNTMAWAPLNAMATPRHG 408
            |..:|       |.:|.|..:..|:.:.|||   :|:.  ..|...|.....|:....|...|.|
 Frog   325 DIPSP-------RKEFSACAIGCKVYITGGRGSENGVS--KDVWVYDTLHEEWSKAAPMLVARFG 380

  Fly   409 LGVAVLEGPLYAVGGHDGWS---------YLNTVERWDPIARTWSYVAPMSSMRSTAGVAVLGGR 464
            .|.|.|:..||.||||...:         .|..||::||:...|:.|||:....|.|.|.....:
 Frog   381 HGSAELKHCLYVVGGHTAATGCLPASPSVSLKQVEQYDPVTNKWTMVAPLREGVSNAAVVSAKLK 445

  Fly   465 LYAVGGRDGSVCH---RSIECYDPHTNKWSLLAPMNRRRGGVGVTVANGFLYALGGHDCPASNPM 526
            |:|.||.  ||.|   ..::||||..|:||:.|...:........|....::.:|| |...|
 Frog   446 LFAFGGT--SVSHDKLPKVQCYDPSENRWSVPATCPQPWRYTAAAVLGTQIFIMGG-DTEFS--- 504

  Fly   527 VCRTETVERYDPATDTWTLICSLALGRDAIGCALLGDRLIVVGGYDGNHALKSVEEYDPVRNGWN 591
            .|   :..:::..|..||....:...|.:......|::|.|||||.|....|:::.|||..:.||
 Frog   505 AC---SAYKFNSETYQWTKAGDVTAKRMSCHAVASGNKLFVVGGYFGIQRCKTLDCYDPTLDVWN 566

  Fly   592 -------ELAPMAF 598
                   .|.|.||
 Frog   567 SITTVPYSLIPTAF 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17754	NP_572549.2	PHA03098	71..591	CDD:222983	161/543 (30%)
		KELCH repeat	359..402	CDD:276965	11/45 (24%)
		KELCH repeat	406..449	CDD:276965	19/51 (37%)
		KELCH repeat	453..497	CDD:276965	18/46 (39%)
		KELCH repeat	500..549	CDD:276965	9/48 (19%)
		KELCH repeat	553..596	CDD:276965	16/49 (33%)
enc1	XP_002934870.1	BTB_POZ_KLHL37_ENC1	6..152	CDD:349576	53/147 (36%)
		PHA03098	60..566	CDD:222983	155/523 (30%)
		BACK_KLHL37_ENC1	145..242	CDD:350590	33/96 (34%)
		KELCH repeat	330..374	CDD:276965	11/45 (24%)
		KELCH repeat	378..431	CDD:276965	20/52 (38%)
		KELCH repeat	434..480	CDD:276965	18/47 (38%)
		KELCH repeat	528..573	CDD:276965	15/44 (34%)