DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17754 and klhl20

DIOPT Version :9

Sequence 1:	NP_572549.2	Gene:	CG17754 / 31873	FlyBaseID:	FBgn0030114	Length:	654	Species:	Drosophila melanogaster
Sequence 2:	NP_001135481.1	Gene:	klhl20 / 100216018	XenbaseID:	XB-GENE-960635	Length:	234	Species:	Xenopus tropicalis

Alignment Length:	164	Identity:	74/164 - (45%)
Similarity:	102/164 - (62%)	Gaps:	2/164 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 HADNILKRMQLYVDSQQLCDVVLIAGIDGKRVPAHRLVLSASSAYFSAMFTGSLRETKEQEVTLG 121
            |....|:.:.|....::||||||:.|  .|::.|||::|||.|.||.|||||.|.|:::.||.:.
Frog    50 HPRQTLEVINLLRKHRELCDVVLVVG--AKKIYAHRVILSACSPYFRAMFTGELAESRQTEVVIR 112

  Fly   122 EVHGDALHLLVQYCYTGFIEMREDTVETLLATACLLQLNAVVTACCNFLARQLHPSNCLGFAFFA 186
            ::...|:.||:.:.||..|.:.|..|:|||..||||||..:..|||.||.|||.||||||...||
Frog   113 DIDERAMELLIDFSYTSQITVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDPSNCLGIRAFA 177

  Fly   187 EQQSCTTLLRLAQAYTCQYFMQVCQNQEFFQLNA 220
            :..||..|||:|..:|...|.:|..:..|.:||:
Frog   178 DTHSCRELLRIADKFTQHNFQEVRDSVLFRKLNS 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17754	NP_572549.2	BTB	70..170	CDD:279045	46/99 (46%)
		PHA03098	71..591	CDD:222983	71/150 (47%)
		BACK	179..281	CDD:285009	17/42 (40%)
		Kelch	323..369	CDD:128874
		KELCH repeat	359..402	CDD:276965
		Kelch	370..416	CDD:128874
		KELCH repeat	406..449	CDD:276965
		Kelch	418..463	CDD:128874
		KELCH repeat	453..497	CDD:276965
		Kelch	464..510	CDD:128874
		Kelch_1	499..546	CDD:279660
		KELCH repeat	500..549	CDD:276965
		KELCH repeat	553..596	CDD:276965
		Kelch	564..610	CDD:128874
klhl20	NP_001135481.1	BTB	59..162	CDD:279045	48/104 (46%)
		BTB	69..165	CDD:197585	47/97 (48%)
		BACK_Kelch	165..>203	CDD:269808	18/37 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D312716at33208
OrthoFinder	1	1.000	-	-		FOG0000036
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X9
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010