Protein Alignment Takl1 and Ripk2

DIOPT Version :10

• Sequence 1: NP_732554.1
• Gene: Takl1 / 318725
• FlyBaseID: FBgn0046689
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_001178794.1
• Gene: Ripk2 / 362491
• RGDID: 1309167
• Length: 539
• Species: Rattus norvegicus
• Alignment Length: 338
• Identity: 91/338 - (26%)
• Similarity: 160/338 - (47%)
• Gaps: 72/338 - (21%)

  Fly    11 KLSE-KFLGAGSGGAVRKATFQNQEIAVKIFDFLEETIKKNAER-EITHLSEIDHE----NVIRV 69
            ||:: .:|..|:.|.|..|...:..:.|.:......|...::|| :|...:||.|:    .::.:
  Rat    17 KLADLHYLSRGASGTVSSARHADWRVRVAVKHLHIHTPLLDSERNDILREAEILHKARFSYILPI 81

  Fly    70 IGRASNGKKDYLLMEYLEEGSLHNYLYGDDKWEYTVEQAVRWAL------QCAKALAYLHSLDRP 128
            :|..:..:...::.||:..|||:..|:  .|.||   ..:.|.|      :.|..:.|||:::.|
  Rat    82 LGICNEPEFLGIVTEYMPNGSLNELLH--RKTEY---PEIAWPLRFRILHEIALGVNYLHNMNPP 141

  Fly   129 IVHRDIKPQNMLLYNQHEDLKICDFGLA----TDMSNNKTDMQ----GTLRYMAPE--------- 176
            ::|.|:|.||:||.|:.. :||.||||:    ..:|.:::...    ||:.||.||
  Rat   142 LLHHDLKTQNILLDNEFH-VKIADFGLSKWRMMSLSQSRSYKSAPEGGTIIYMPPENYEPGQKSR 205

  Fly   177 -AIKHLKYTAKCDVYSFGIMLWELMTRQLPYSHLENPNSQYAIMKAISSG-------EKLPMEAV 233
             ::||       |:||:.:::||:::|:.|:..:.||   ..||.::|.|       |.||.
  Rat   206 ASVKH-------DIYSYAVIMWEVLSRKQPFEEVTNP---LQIMYSVSQGHRPNTSEENLPF--- 257

  Fly   234 RSDCP-EGIK-QLMECCMDINPEKRPS----MKEIEKFLGEQYESGTDEDFIKPLDEDTVAVVTY 292
              |.| .|:. .|::.....||::|||    :.|:|..| ..:|   |..|:    |..:.:...
  Rat   258 --DIPHRGLMISLIQSGWAQNPDERPSFLKCLIELEPVL-RTFE---DITFL----EAVIQLKKS 312

  Fly   293 HVDSSGSRIMRVD 305
            .:.|:.|.|...|
  Rat   313 KIQSASSTIHLCD 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Takl1	NP_732554.1	STKc_TAK1	17..274	CDD:270960	82/298 (28%)
Ripk2	NP_001178794.1	STKc_RIP2	20..303	CDD:270928	83/307 (27%)
		CARD_RIP2_CARD3	437..523	CDD:176764