Protein Alignment Takl1 and Ankk1

DIOPT Version :10

• Sequence 1: NP_732554.1
• Gene: Takl1 / 318725
• FlyBaseID: FBgn0046689
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_001363880.1
• Gene: Ankk1 / 244859
• MGIID: 3045301
• Length: 746
• Species: Mus musculus
• Alignment Length: 375
• Identity: 97/375 - (25%)
• Similarity: 168/375 - (44%)
• Gaps: 91/375 - (24%)

  Fly     7 FAEVKLSEKFLGAGSGGAVRKATFQ------NQEIAVKIFDFLEETIKKNAEREITHLSE----- 60
            |......|::....|||..:  .||      ..:.|:|....|:   |:....|:|.|.|
Mouse    28 FTRDDFEEEWHLVASGGFSK--VFQARHKRWRTQYAIKCSPCLQ---KETTSSEVTCLFEEAVKM 87

  Fly    61 --IDHENVIRVIG--RASNGKKDYLLMEYLEEGSLHNYLYGDDKWEYTVEQAVRWAL------QC 115
              |..::::.:.|  :...|    ::||::..|||...|         ...::.|.|      :.
Mouse    88 EKIKFQHIVSIYGVCKQPLG----IVMEFMASGSLEKTL---------PTHSLCWPLKLRIIHET 139

  Fly   116 AKALAYLHSLDRPIVHRDIKPQNMLL-YNQHEDLKICDFGLATDMSNN-------KTDMQGTLRY 172
            :.|:.:|||:..|::|.|:||.|:|| .|.|  :||.||||:..|..:       ::.::|||.|
Mouse   140 SLAMNFLHSIKPPLLHLDLKPGNILLDNNMH--VKISDFGLSKWMEQSTQKQYIERSALRGTLSY 202

  Fly   173 MAPEA-IKHLKYTA-KCDVYSFGIMLWELMTRQLPYSHLENPNSQYAIMKAISSGEKLPMEAVRS 235
            :.||. :::.|... :.|||||.|::||::|::.||:.|    :...|:..:::|.:..::.|..
Mouse   203 IPPEMFLENNKAPGPEYDVYSFAIVIWEILTQKKPYAGL----NMMTIIIRVAAGMRPSLQDVSD 263

  Fly   236 DCPEGIKQ---LMECCMDINPEKRPSMKEIEKFLGEQYESGTD---EDFIKPLDEDTVAVVTYHV 294
            :.||.:.|   ||:.|.|.:|:|||.      ||....|  ||   ..|..|:.:.....:|..|
Mouse   264 EWPEEVHQMVNLMKRCWDQDPKKRPC------FLNVAVE--TDMLLSLFQSPMTDPGCEALTQKV 320

  Fly   295 DSSGSRIMRVDFWRHQLPSIRMTFPIVKREAERLGKTVVREMAKAAADGD 344
            ...              ||:        .:..::.|.|.:|:|.:|...|
Mouse   321 SCK--------------PSL--------SQPHKVSKEVNQEIADSAVSSD 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Takl1	NP_732554.1	STKc_TAK1	17..274	CDD:270960	81/290 (28%)
Ankk1	NP_001363880.1	Protein Kinases, catalytic domain	37..305	CDD:473864	83/299 (28%)
		ANKYR	353..630	CDD:440430
		ANK 1	370..399
		ANK repeat	373..401	CDD:293786
		ANK repeat	403..434	CDD:293786
		ANK 2	403..432
		ANK repeat	436..467	CDD:293786
		ANK 3	436..465
		ANK 4	469..498
		ANK repeat	469..497	CDD:293786
		ANK repeat	502..532	CDD:293786
		ANK 5	502..531
		ANK 6	535..564
		ANK repeat	537..566	CDD:293786
		ANKYR	555..>744	CDD:440430
		ANK repeat	568..599	CDD:293786
		ANK 7	568..597
		ANK 8	601..630
		ANK repeat	602..632	CDD:293786
		ANK repeat	634..665	CDD:293786
		ANK 9	634..663
		ANK repeat	667..698	CDD:293786
		ANK 10	667..696
		ANK repeat	700..730	CDD:293786
		ANK 11	700..729