Protein Alignment Takl1 and Blk

DIOPT Version :10

• Sequence 1: NP_732554.1
• Gene: Takl1 / 318725
• FlyBaseID: FBgn0046689
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_031575.2
• Gene: Blk / 12143
• MGIID: 88169
• Length: 499
• Species: Mus musculus
• Alignment Length: 290
• Identity: 77/290 - (26%)
• Similarity: 147/290 - (50%)
• Gaps: 43/290 - (14%)

  Fly    10 VKLSEKFLGAGSGGAVRKATFQ-NQEIAVKIFDFLEETIKKNAEREITHLSE------IDHENVI 67
            :||..| ||:|..|.|....:: |.::|:|       |:|:........|.|      :.||.::
Mouse   235 LKLVRK-LGSGQFGEVWMGYYKNNMKVAIK-------TLKEGTMSPEAFLGEANVMKTLQHERLV 291

  Fly    68 RVIGRASNGKKDYLLMEYLEEGSLHNYLYGDDKWEYTVEQAVRWALQCAKALAYLHSLDRPIVHR 132
            |:....:. :..|::.||:..|.|.::|..|:....::.:.:..:.|.|:.:||:..::.  :||
Mouse   292 RLYAVVTR-EPIYIVTEYMARGCLLDFLKTDEGSRLSLPRLIDMSAQVAEGMAYIERMNS--IHR 353

  Fly   133 DIKPQNMLLYNQHEDL--KICDFGLATDMSNNKTDMQGT---LRYMAPEAIKHLKYTAKCDVYSF 192
            |::..|:|:   .|.|  ||.|||||..:.:..|..:|.   :::.|||||....:|.|.||:||
Mouse   354 DLRAANILV---SETLCCKIADFGLARIIDSEYTAQEGAKFPIKWTAPEAIHFGVFTIKADVWSF 415

  Fly   193 GIMLWELMT-RQLPYSHLENPNSQYAIMKAISSGEKLPMEAVRSDCPEG-----IKQLMECCMDI 251
            |::|.|::| .::||..:.||.    :::::..|.::|       |||.     ...::..|...
Mouse   416 GVLLMEIVTYGRVPYPGMSNPE----VIRSLEHGYRMP-------CPETCPPELYNDIITECWRG 469

  Fly   252 NPEKRPSMKEIEKFLGEQYESGTDEDFIKP 281
            .||:||:.:.::..|.:.|.:...:..::|
Mouse   470 RPEERPTFEFLQSVLEDFYTATEGQYELQP 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Takl1	NP_732554.1	STKc_TAK1	17..274	CDD:270960	73/274 (27%)
Blk	NP_031575.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..34
		SH3	56..109	CDD:473055
		SH2_Src_Blk	114..213	CDD:198234
		Protein Kinases, catalytic domain	227..490	CDD:473864	76/279 (27%)