Protein Alignment Gba1b and gba-3

DIOPT Version :9

• Sequence 1: NP_001097888.1
• Gene: Gba1b / 318721
• FlyBaseID: FBgn0051414
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001255965.1
• Gene: gba-3 / 178535
• WormBaseID: WBGene00008706
• Length: 525
• Species: Caenorhabditis elegans
• Alignment Length: 551
• Identity: 187/551 - (33%)
• Similarity: 270/551 - (49%)
• Gaps: 92/551 - (16%)

  Fly    39 VCVCNSTYCDYLEPPQLTDISQ--IVVISSSKDGLRFKKTTGDLSKKKPITIDDKQFTDENFKAD 101
            |||||:|:||.:||  :.:|::  .:|..||.||.|.|:.:..:.:|
 Worm    41 VCVCNATFCDEIEP--IGEIAEGKAIVYRSSLDGDRLKRMSMKMKEK------------------ 85

  Fly   102 AIVVDQERAWLQLANIPQSLFINASIKTYRIFVKREQSFQNVSIFGGAFTGTVSYLLKELPVELQ 166
                               |..|.|:.. .|.:...:.|||:..||||||.:.......|...||
 Worm    86 -------------------LRKNESVNV-TITIDASERFQNIFGFGGAFTDSAGDQFVSLSETLQ 130

  Fly   167 DHVYRSYFHPVGIAYNTIRMSIGGSDFDMEPWAYNELPLHDP-KLSNFTELDPRDLQ-KVEQLKR 229
            :::..|||...|:.||..|:.|...||....::|::  :||. :|.:|. |...||: |:..:|
 Worm   131 NYIVDSYFGKNGLEYNIGRVPIASCDFSTHEYSYDD--VHDDFELKHFA-LPDEDLKLKIPFIK- 191

  Fly   230 LKIIGKVD-SLKIMGAAWSAPTWMKSNNRWTGFGQLKSE--YYQTWALYHLKFLELMRSKNMPIW 291
             |.|.|.: ::::..:.||||.|||...|..|.|.::::  .||.:|.|..||.|...|..:..|
 Worm   192 -KAIEKTEGNIQLFASPWSAPGWMKVTGRMRGGGAMRNDKRVYQAYADYFFKFFEAYSSHAITFW 255

  Fly   292 AISTGNEPLNGVIGFFFVHFMSMGWTPWQ--------QAIWLNDNLGPTIRNSAES---KVLIFG 345
            .::..|||..|.         .|.|. ||        ...:|...|||.::.:..:   ||::.
 Worm   256 GLTIQNEPSTGA---------DMAWR-WQTMNYTAETMRDFLKKYLGPKLKENKLTETLKVMVL- 309

  Fly   346 NDDQRYTYPTW----FRKMRSSRNNSLNYLDGLAVHWYWDELIGPQLIDQAHTDMPNKLLLNTES 406
             ||.|...|.|    |....:::     |.||:|||||.:......|:|......|.|.:..||:
 Worm   310 -DDGRGLLPGWADTIFNDPEATK-----YADGVAVHWYGNLYSPAVLLDITQRHHPTKFIFGTEA 368

  Fly   407 CIGDKPWQTHGPELGSWQRGESYMRAYTQDLTHNFNGWLDWNLVLDEQGGPNYVKNFVDAPIIVN 471
            |.|  .:..|||.:|.|.|.|||......||.|:..||.||||.|||.||||:..|.||:|||||
 Worm   369 CAG--YFGHHGPIMGDWFRAESYADDIITDLNHHVTGWTDWNLCLDETGGPNWAYNVVDSPIIVN 431

  Fly   472 ATSRSEIYKQPIFYAIGHFSKFLPPDSVRIETRIE-NQSNPFTQLSVVGFQRPDGSVALIIYNGQ 535
            .|:: |.||||:|||:||||||||..|.|:.|:|| |.:...|.:.:.|.:|    ..:|:....
 Worm   432 RTAQ-EFYKQPMFYALGHFSKFLPRGSTRVFTKIEGNLAVSATSVVIEGGRR----ATVILSKAS 491

  Fly   536 NLPVDVTLDDSQRGAIQLRLPPRSWHTVLYK 566
            |..:...:|.|...:|.|.|||||.|||::|
 Worm   492 NSLLTRIVDSSTGFSIVLNLPPRSIHTVIWK 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gba1b	NP_001097888.1	Glyco_hydro_30	28..559	CDD:304972	181/542 (33%)
gba-3	NP_001255965.1	Glyco_hydro_30	28..521	CDD:304972	186/548 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166002
Domainoid	1	1.000	225	1.000	Domainoid score	I1442
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	274	1.000	Inparanoid score	I1794
Isobase	1	0.950	-	0	Normalized mean entropy	S4252
OMA	1	1.010	-	-		QHG62715
OrthoDB	1	1.010	-	-		D206521at33208
OrthoFinder	1	1.000	-	-		FOG0004266
OrthoInspector	1	1.000	-	-		mtm4803
orthoMCL	1	0.900	-	-		OOG6_102859
Panther	1	1.100	-	-	LDO	PTHR11069
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3226
SonicParanoid	1	1.000	-	-		X3004
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.890