Protein Alignment Gba1b and gba-1

DIOPT Version :9

• Sequence 1: NP_001097888.1
• Gene: Gba1b / 318721
• FlyBaseID: FBgn0051414
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001040750.1
• Gene: gba-1 / 173574
• WormBaseID: WBGene00016335
• Length: 523
• Species: Caenorhabditis elegans
• Alignment Length: 582
• Identity: 162/582 - (27%)
• Similarity: 249/582 - (42%)
• Gaps: 103/582 - (17%)

  Fly    11 FLTTVIAISAGAPDWQLPCDLRETSHGSVCVCNSTYCDYLEPPQLTDISQIVVISSSKDGLRFKK 75
            ||......|..|.|    |..:....|:||||:...||.:.|..:| :.|..:.::|..|.|..:
 Worm    12 FLAVFGVDSVRAAD----CTEKTFKTGTVCVCSLDSCDEIPPLDIT-MGQAALYTTSHTGARLHR 71

  Fly    76 TTGDLSKKKPITIDDKQFTDENFKADAI-VVDQERAWLQLANIPQSLFINASIKTYRIFVKREQS 139
                                     |.| ..|.|                 ...|..:.:...:.
 Worm    72 -------------------------DVIYATDTE-----------------PFGTLHMTIDSSKK 94

  Fly   140 FQNVSIFGGAFTGTVSYLLKELPVELQDHVYRSYFHPVGIAYNTIRMSIGGSDFDMEPWAYNELP 204
            :|.:..||..|:......||.||.:|.|.:.:.||...|:.....|:.|..:||....::||::
 Worm    95 YQTIQGFGSTFSDASGANLKSLPDKLSDLIMKQYFSDTGLNLQFGRVPIASTDFSGRVYSYNDV- 158

  Fly   205 LHDPKLSNFTELDPRDLQ-KVEQLKRLKIIGKVDSLKIMGAAWSAPTWMKSNNRWTGFGQLKSE- 267
            .:|..:.|| .|...|.| |:..:|..:...  .:||:..|.|:||.|:|:....||.|.|..:
 Worm   159 ANDYSMQNF-NLTKEDFQWKIPYIKNAQKYN--PNLKLFAAPWAAPGWLKTTKEMTGPGALNGKA 220

  Fly   268 ---YYQTWALYHLKFLELMRSKNMPIWAISTGNEPL------NGVIGFFFVHFMSMGWTPWQQAI 323
               |:|.:|.|.::|||......:..|.:||.|:|.      |.:....|        |...|..
 Worm   221 GDNYHQAYAKYFVRFLEEYGKSGISFWGLSTQNQPTLGSDKKNKIQSTLF--------TAETQRD 277

  Fly   324 WLNDNLGPTIRNSA---ESKVLIFGNDDQRYTYPTWFRKMRSSRNNSLNYLDGLAVHWYWDELIG 385
            ::..:|||.:..|:   :.|:||.  ||.|...|.|...:.:.. ::..|:.|:.||.|.|....
 Worm   278 FIKTDLGPALAASSSGKDVKLLIL--DDNRGNLPKWADTVLNDM-DAAKYVGGIGVHAYQDGETD 339

  Fly   386 PQLIDQAHTDMPNKLLLNTESCIGDKPWQTHGPELGSWQRGESYMRAYTQDLTHNFN----GWLD 446
            ..| |:.|...||..:|.||:..|.....|| .:.|:|.|...    ...|:..|.|    ||.:
 Worm   340 NHL-DETHKKHPNFFILGTEASEGYGSKDTH-VDYGNWDRAAD----TASDILDNMNNWMTGWTE 398

  Fly   447 WNLVLDEQGGPNYVKNFVDAPIIVNATSRSEIYKQPIFYAIGHFSKFLPPDSVRIE---TRIENQ 508
            .||:||..|||::|.::.|||:|. ..:.::.||||:||||.|||.|:.|.:|||:   ..||
 Worm   399 RNLILDALGGPSWVSDYTDAPVIA-FPAMAQFYKQPMFYAIAHFSHFIKPGAVRIDHSLNVIE-- 460

  Fly   509 SNPFTQLSVVGFQRPDGSVALIIYNGQNL---PVDVTLDDS--QRGAIQLRLPPRSWHTVLY 565
                .::....|..||||..:::.|..:|   ...|.:.|:  .|......||.|: .|.||
 Worm   461 ----LEVETTAFLNPDGSKVIVMLNKGSLVSTEHTVVVQDAADSRNHYHFTLPHRA-ITTLY 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gba1b	NP_001097888.1	Glyco_hydro_30	28..559	CDD:304972	153/557 (27%)
gba-1	NP_001040750.1	Glyco_hydro_30	23..519	CDD:110998	159/571 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166003
Domainoid	1	1.000	225	1.000	Domainoid score	I1442
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	274	1.000	Inparanoid score	I1794
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62715
OrthoDB	1	1.010	-	-		D206521at33208
OrthoFinder	1	1.000	-	-		FOG0004266
OrthoInspector	1	1.000	-	-		mtm4803
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3004
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.910